Results 61 to 70 of about 92,598 (353)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

European social fund in Czech Republic and its contribution to development of adult education [PDF]

open access: yes, 2009
This bachelor thesis focuses on European social fund and its contribution to development of adult education in Czech Republic. The contribution is observed through the outcomes of projects, which were - thanks to European social fund - realized in past 4
Tichý, Karel
core  

The Role of Cohesion Policy in the Development of Romania

open access: yesStudies in Business and Economics, 2019
Cohesion is a common European value. The E.U.’s cohesion policy is and will remain an essential financing instrument for various multiannual development programs, for both member states and regions.
Paul Lucian
doaj   +1 more source

MACROECONOMIC ANALYSIS OF THE COHESION FUND IN CENTRAL AND EASTERN EUROPE AT REGIONAL LEVEL [PDF]

open access: yesAnnals of the University of Oradea: Economic Science
European funds and their impact at regional level have gained significant attention because there is a desire to distribute funds as efficiently as possible and in such a way that regions benefit in proportion to their needs.
Ligia HADASA PRICOPIUC
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The shape of the European Social Fund in Ireland, 2000 to 2006

open access: yes, 2000
SIGLEAvailable from British Library Document Supply Centre-DSC:m00/39986 / BLDSC - British Library Document Supply CentreGBUnited ...
European Social Fund (ESF), Dublin (Ireland)
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Worrying Labour Market Tendencies in the European Union [PDF]

open access: yesRomanian Journal of European Affairs, 2018
The authors examine the developments that have characterized the European Union labour market in the past decades, relying mainly on Eurostat data. They focus on the tendencies of employment and unemployment in general, the changing conditions of work ...
Annamaria Artner, Krisztina Sőreg
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Convergence Instruments of Western Balkan Countries

open access: yesEconomic Analysis, 2017
The fundamental objective of the EU regional policy is to reduce differences in development between regions in Europe. EU is directing structural funds to the regions which need help, and in that way EU helps to raise the level of employment and living ...
Marko Tomljanović   +2 more
doaj  

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