Results 61 to 70 of about 923,367 (308)
Simulation of production processes with Plant Simulation
International Journal of Engineering and Management Sciences, 2019 This article presents the modelling of interconnected companies’ logistic processes with Tecnomatix Plant Simulation by Siemens. It has two main parts. The first contains the details of recognition including simulation.
Máté Miltényi, Levente Czégé
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Endoglin-mediated angiogenic responses are regulated by its cytosolic domain [PDF]
, 2015 1 p.This work was supported by grants from Czech Science foundation GACR number 15-24015S, the Grant Agency of Charles University in Prague (1284214/C and 1158413/C), Charles University in Prague (SVV/2014/260064), European Regional Development Fund ...
Bernabéu, Carmelo +6 more
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Analysis of the Impact of the European Social Fund on the SME Sector in Poland
Problemy Zarządzania, 2020 The aim of this article is to assess the impact of the European Social Fund (ESF) on the development of human capital in the small and medium-sized enterprise (SME) sector.
Przemysław Dubel
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Central and eastern european social model [PDF]
The 10 former communist countries from Central and Eastern Europe have inherited similar social protection systems, specific to an ethatist economy, and faced similar issues along the transition to market economy. Distinct in Europe through common traits,
Rotaru, Marius-Petre
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Revista Catalana de Dret Públic, 2019 European policy-making has focused on economic and budgetary policies in the aftermath of the financial crisis of 2007-2008 and the austerity programmes that ensued.
Stephan Grohs
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
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CBU International Conference Proceedings, 2014 This article focuses on fund financing management of one of the utmost important European Union funds, the European Social Fund (ESF), and its implementation in Romania in its post adherence period (2007-2013). In this respect, the main aspects regarding the management and implementation of this program in Romania, as compared to other European ...
Tiberiu Foris, Diana Foris
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source