Post-Apartheid National Spatial Development Planning in South Africa - A Brief History [PDF]
Since coming to power in 1994 successive ANC-governments have engaged in a series of attempts at national spatial development planning in South Africa. These engagements have received scant treatment in the planning literature.
Oranje, Mark
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Determinants and Implications of the Tourism Multiplier Effect in EU Economies. Towards a Core-Periphery Pattern? [PDF]
Tourism is considered an opportunity for ensuring sustainable growth and reducing economic gaps for many less developed countries and regions. Being one of the most dynamics industries, tourism proves to be strongly resilient, with a high level of ...
Gabriela Carmen Pascariu +1 more
doaj +1 more source
ESPON Project 2.3.1., Application and effects of the ESDP in the Member States. Second Interim Report [PDF]
This Second Interim Report includes the preliminary results of the project, "Application and Effects of the ESDP in the Member States" within the ESPON Programme 2000-2006.
Cotella, Giancarlo +5 more
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Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
The architecture of subject [PDF]
This essay defines material and symbolic implications of linear perspective in modern architecture. First is seen as aesthetical method, which appears in architectural drawings since beginning of European Renaissance.
Mitrovic Jelena
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Conforming and performing planning systems in Europe: an unbearable cohabitation [PDF]
Two planning system models currently cohabit in Europe: a more traditional and widespread one, aspiring to ‘conform' single projects to a collective strategy; and a different and less institutionalised one, promoting those projects capable of ‘performing'
Janin Rivolin, U.
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Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Cohesion and subsidiarity: towards good territorial governance in Europe [PDF]
The message of this paper is twofold: (a) the pursuit of territorial cohesion, the importance of which the new European Constitution recognises, requires coordination of national planning systems; and (b) subsidiarity, a Community principle usually ...
Janin Rivolin, U.
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