Results 71 to 80 of about 9,614 (253)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Europeanisation Through Mobility:Visa Liberalisation and Citizenship Regimes in the Western Balkans [PDF]

open access: yes, 2012
This paper examines the implications of the visa liberalisation dialogues which took place between the European Commission and national governments of the Western Balkans for the citizenship regimes of the countries concerned.
Kacarska, Simonida
core  

EUROPEANISATION: AN ANSWER TO GLOBALISATION

open access: yesAnkara Avrupa Çalışmaları Dergisi, 2012
Avrupalılaşma, Avrupa Birliği tarafından şekillendirilen toplumsal ve ekonomik değişimlerin büyüklüğü yüzünden önemli bir dünya düzeni olarak ortaya çıkmaktadır.
Füsun Özerdem
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Sharing Water on the Iberian Peninsula: A Europeanisation Approach to Explaining Transboundary Cooperation

open access: yesWater Alternatives, 2011
This paper applies the Europeanisation perspective to the policy change evident in the 1998 Convention on Cooperation for the Protection and Sustainable Use of the Waters of the Spanish-Portuguese Basins (Albufeira convention).
Jeanie J. Bukowski
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Direct and indirect europeanisation of national administrative systems. Implementation and spillover effects of the environmental information directives in a comparative perspective

open access: yesRevista Catalana de Dret Públic, 2018
Until the 1980s, a culture of administrative secrecy prevailed in most European countries. This general approach only changed with the adoption of the first administrative procedure laws, which codified a right of access to files, albeit usually limited ...
Cristina Fraenkel-Haeberle   +1 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Justice Reform or Facade Reform: The case of the Western Balkans

open access: yesPolitics in Central Europe, 2020
EU transformative power is put into question and constantly challenged by the political actions of leaders in the Western Balkans. Although the political elites in this region have internalised a pro-European discourse, they are still guided and governed
Halili Zenun
doaj   +1 more source

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