Results 121 to 130 of about 14,145 (312)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

The Internalization of the European Administrative Space - principles in national public administrations. Study Case: Romania [PDF]

open access: yes, 2011
Among different sociological concepts and theories applicable to the study of the process of Europeanization of public administration, internalization is but seldom to be encountered.
Matei, Lucica   +2 more
core  

Europeanization

open access: yes, 2020
Europeanization refers to the mutual influence of the European Union (EU) and its member states, to interactions within and between member states driven by the EU, and to the effect of the EU on EU applicant states.
Dosenrode, Søren, Søren Dosenrode
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

CONNECTING THE ENLARGEMENT PROCESS WITH THE EUROPEANIZATION THEORY (THE CASE OF TURKEY) [PDF]

open access: yes
Europeanization is one of the theoretical instruments which had a vital influence on candidate countries for EU membership. Due to its aspirations of becoming member of the European Union (EU) and in its attempt to fulfil the Copenhagen criteria, Turkey ...
Teodor Lucian Moga
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

"Europeanization of the core executive in the transition from circumstances of EU accession to full EU membership" [PDF]

open access: yes, 2005
Only recently have the direct and indirect ‘European’ impacts (of political outcomes at the European level) on domestic political systems started to be studied (i.e. Spanou, 1998; Bulmer and Burch, 1998 and 2001; Kassim, Peters and Wright, eds.
Fink-Hafner, Danica.
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

International Relations Theory and European Integration [PDF]

open access: yes
Europeanization; multilevel governance; institutionalism; institutionalisation; policy ...
Tanja Börzel, Thomas Risse
core  

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