Results 61 to 70 of about 36,154 (294)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Europeanization Research

open access: yesCzech Journal of International Relations, 2007
Europeanization Research is a dynamic area of political sciences both internationally and in the Czech Republic. However, despite the popularity of the concept and the still-growing number of conference papers, articles and books devoted to its various ...
Štěpánka Zemanová
doaj  

Derechos sociales y teoría de la integración europea: ubicando la jurisprudencia del TJUE en tres contextos nacionales [PDF]

open access: yes, 2017
This article examines the jurisprudence of the Court of Justice of the European Union (CJEU) concerning the social rights of mobile EU citizens from the perspective of European integration theory.
Mantu, Sandra, Minderhoud, Paul
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

The European Union and party politics in Central Europe [PDF]

open access: yes, 2007
It is only recently that political scientists have begun to focus on the influence of European Union involvement on national parties. Mair's study of the impact of Europe on the parties of Western Europe is now a standard point of reference, and ...
Lewis, Paul
core  

Regulating intimate relationships in the European polity: same-sex unions and policy convergence [PDF]

open access: yes, 2013
Since 1989, twenty-three European countries have implemented same-sex union (SSU) laws. We argue that the political processes leading to the adoption of these policies have been shaped by international influences such as policy harmonization, elite ...
D. Paternotte   +4 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Let's talk about Europe': explaining vertical and horizontal Europeanization in the quality press [PDF]

open access: yes
This paper contributes to the ongoing quest for a European public sphere understood as a structural transformation of national media debates. The process of Europeanization has a vertical and a horizontal dimension: an increased focus on the EU as well ...
Brüggemann, Michael   +1 more
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Applying the Concept of Europeanization to the Study of Foreign Policy: Dimensions and Mechanisms [PDF]

open access: yes
Recent years have witnessed a growing interest in applying the Europeanization concept to the study of foreign policy. Discussing how foreign policy Europeanization relates to Europeanization research in other areas of EU governance as well as to ...
Patrick Müller and Nicole Alecu de Flers
core  

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