Results 71 to 80 of about 1,177 (267)
The EU Economic Crisis – Reflections in the Opinions of Citizens and Experts [PDF]
Romanian Journal of European Affairs, 2013 Perhaps one of the most important challenges that the EU is currently facing is that of building public support for the Union project as the economic crisis develops, confidence in the EU future is weakened and member states turn to their own boundaries.
Nicoleta Corbu, Oana Ştefăniţă
doaj
Romii din România postdecembristă
Sfera Politicii, 2021 The subject of the relationship between Roma and the State in post-communist Romania can be representative in order to measure the proximity and also the distance of the Romanian society from two major objectives: the democratization, in the 90s, and the
Florinela Giurgea
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Науково-інформаційний вісник Івано-Франківського університету права імені Короля Данила ГалицькогоPurpose. The purpose of the study is to determine the main directions of modernization of the Regulation of the Verkhovna Rada of Ukraine (hereinafter referred to as the Regulation) in the context of the key guidelines of parliamentary reform at the ...
Linetskyi S.
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
European Union and European Germany
Oeconomia Copernicana, 2015 We analyze the correlation between the European integration and incorporating Germany into the process of European cooperation. We point out that the European integration after WWII was determined by the creation of the European Coal and Steel Community in the year 1951. This Community made it possible to control the steel industry of the Member States
Jerzy Menkes, Elżbieta Czarny
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source