Results 141 to 150 of about 42,499 (267)

Lost in Translation: Why Biologic Therapies for Intervertebral Disc Degeneration and Low Back Pain Have Not Reached the Clinic (Yet)

JOR SPINE, Volume 9, Issue 3, September 2026.
From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.
Luca Ambrosio, Jordy Schol, Clara Ruiz‐Fernandez, Vincenzo Denaro, Gianluca Vadalà, Daisuke Sakai   +5 more
wiley   +1 more source

A comparison of EuroQol 5-Dimension health-related utilities using Italian, UK, and US preference weights in a patient sample

, 2016
Adelaide Mozzi,1 Michela Meregaglia,2 Carlo Lazzaro,3 Valentina Tornatore,4 Maurizio Belfiglio,4 Giovanni Fattore,1,2 1Department of Policy Analysis and Public Management, 2Centre for Research on Health and Social Care Management (CeRGAS), Bocconi ...
Fattore G, Mozzi A, Tornatore V, Meregaglia M, Lazzaro C, Belfiglio M   +5 more
core  

UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Autism Spectrum Disorder

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
A case series studying outcomes up to 18 months in autistic patients from the UK Medical Cannabis Registry. ABSTRACT Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with distressed behaviors and psychological challenges.
Arushika Aggarwal, Simon Erridge, Madhur Varadpande, Evonne Clarke, Katy McLachlan, Ross Coomber, Muhammed Asghar, Urmila Bhoskar, Matthieu Crews, Andrea De Angelis, Muhammad Imran, Fariha Kamal, Laura Korb, Gracia Mwimba, Simmi Sachdeva‐Mohan, Gabriel Shaya, James J. Rucker, Mikael H. Sodergren   +17 more
wiley   +1 more source

Developing a Set of Core Patient‐Reported Outcomes for Kidney Replacement Therapy: A Modified Delphi Study

Journal of Renal Care, Volume 52, Issue 3, September 2026.
ABSTRACT Background Patient‐reported outcome measures can highlight the impact of kidney failure and kidney replacement therapy on a person's health‐related quality of life and symptom burden. But their implementation is limited and heterogeneous within Australian and New Zealand kidney care.
Jessica Nikolovski, Brendan Smyth, Shyamsundar Muthuramalingam, Stephen McDonald, Jessica Roydhouse, Olalekan Lee Aiyegbusi, Claudia Rutherford, Amy Luchterhand, Paolo Cardelli, Rachael L. Morton, the ANZDATA PROMs Delphi Group   +10 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, Volume 73, Issue 8, August 2026.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

A consistency test of the time trade-off [PDF]

This paper tests the internal consistency of time trade-off utilities. We find significant violations of consistency in the direction predicted by loss aversion. The violations disappear for higher gauge durations.
José Luis Pinto, Han Bleichrodt, José María Abellán-Perpiñán   +2 more
core  

Long‐Term Quality of Life in 1777 Persons With Hodgkin Lymphoma and 6166 Matched Comparators

American Journal of Hematology, Volume 101, Issue 7, Page 1654-1664, July 2026.
ABSTRACT Survival has improved substantially for patients with Hodgkin lymphoma (HL), but long‐term quality of life (QoL) remains incompletely understood. This was a Danish, nationwide, cross‐sectional study of QoL among persons with a diagnosis of HL matched 1:10 to general population comparators.
Sissel Johanne Godtfredsen, Joachim Baech, Mikkel Porsborg Andersen, Harman Yonis, Paw Jensen, Peter Kamper, Jacob H. Christensen, Rasmus Bo‐Dahl Sørensen, Martin Hutchings, Christian Torp‐Pedersen, Peter Sogaard, Henrik Boggild, Kristian H. Kragholm, Tarec C. El‐Galaly   +13 more
wiley   +1 more source

Clinimetrics: The EuroQol-5 Dimension (EQ-5D)

Journal of Physiotherapy, 2020
Juliana S Oliveira, Alison Hayes
openaire   +2 more sources

Measuring the Effects of Workloss on Productivity With Team Production [PDF]

Using data from a survey of 800 managers in 12 industries, we find empirical support for the hypothesis that the cost associated with missed work varies across jobs according to the ease with which a manager can find a perfect replacement for the absent ...
Sean Nicholson, Helena Szrek, Claire Sharda, Marc V. Pauly, Daniel Polsky   +4 more
core  

Financial Toxicity Associated with Biological Medicines: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 81-93, July 2026.
Financial toxicity, defined as the economic burden experienced by patients due to medication and other healthcare costs and their consequences, such as material, psychosocial and behavioral effects, represents a significant concern for individuals receiving biological medicines.
Laura Sara Maria Saarukka, Kamilla Yamileva, Kari Linden, Anniina Simonen, Anna‐Riia Holmström   +4 more
wiley   +1 more source