Results 51 to 60 of about 260 (130)

SEMISINTESIS DAN KARAKTERISASI ANTIMALARIA BARU TURUNAN EURIKUMANON

JKS (Jurnal Kedokteran Syiah Kuala), 2017
Abstrak. Meluasnya penyebaran resistensi Plasmodium terhadap antimalaria merupakan permasalahan utama dalam pemberantasan malaria.Upaya cepat untuk mengatasi masalah tersebut, salah satunya melalui penemuan dan pengembangan antimalaria barudari tumbuhan ...
Hanifah Yusuf, Kurnia Fitri Jamil, Tristia Rinanda   +2 more
doaj  

Enhancement of eurycomanone biosynthesis in cell culture of longjack (Eurycoma longifolia) by elicitor treatment

Journal of Plant Biotechnology, 2018
In this study, the effect of elicitors such as yeast extract (YE), methyl jasmonate (MeJA) and salicylic acid (SA) on the accumulation of eurycomanone in Eurycoma longifolia cell cultures were investigated. Suspension cells of E. longifolia was cultured in Murashige and Skoog (MS) medium supplemented with 30 g/L sucrose, 1.25 mg/L naphthaleneacetic ...
Nguyen Huu Nhan, Nguyen Hoang Loc
openaire   +2 more sources

Physicochemical Effects of the Major Quassinoids in a Standardized Extract (Fr 2) on the Bioavailability and Pharmacokinetic Properties, and their Implications for Oral Antimalarial Activity

Natural Product Communications, 2011
A simple validated LC-UV method for the phytochemical analysis of four bioactive quassinoids, 13α(21)-epoxyeurycomanone ( EP ), eurycomanone ( EN ), 13α,21-dihydroeurycomanone ( ED ) and eurycomanol ( EL ) in rat plasma following oral (200 mg/kg) and ...
Bin-Seng Low, Chin-Hoe Teh, Kah-Hay Yuen, Kit-Lam Chan   +3 more
doaj   +1 more source

Morphological studies of apoptotic HeLa cells death induced by eurycomanone

Indonesian Journal of Pharmacy, 2018
Eurycomanone is a cytotoxic ingredient found in Eurycoma longifolia Jack. Previous studies have noted its activity against many epithelial cell lines. In this study, eurycomanone had obvious cytotoxic effect on HeLa cells by methylene blue staining assays.
Nurkhasanah, Azimahtol Hawariah Lope Pihie, Jalifah Latip   +2 more
openaire   +1 more source

A Multifaceted Review of Eurycoma longifolia Nutraceutical Bioactives: Production, Extraction, and Analysis in Drugs and Biofluids. [PDF]

ACS Omega, 2023
Farag MA, Ajayi AO, Taleb M, Wang K, Ayoub IM.   +4 more
europepmc   +1 more source

Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds in Eurycoma longifolia Jack-Current Status and Future Perspectives. [PDF]

Plants (Basel), 2023
Sale S, Subramaniam S, Mad' Atari MF.
europepmc   +1 more source

Isolasi, Validasi Metode dan Optimasi Awal Proses Ekstraksi Senyawa Penanda Eurycomanon dari Akar Tanaman Pasak Bumi (Eurycoma longifolia)

Chimica et Natura Acta, 2017
Pasak Bumi (Eurycoma longifolia) secara etnofarmakologi digunakan sebagai obat herbal tradisional yang digunakan untuk afrodisiak dan vitalitas. Eurycomanon digunakan sebagai senyawa penanda dari ekstrak akar pasak bumi, namun kadar yang diperbolehkan dalam ekstrak pasak bumi sesuai standar Malaysia pada kisaran 0,8–1,5%, karena sifatnya yang toksik ...
Prasetyawan Yunianto, Nurhadi Nurhadi, Agus Supriyono   +2 more
openaire   +2 more sources

Subcritical Water Extraction (SWE) OF Eurycomanone and Eurycomanol from Roots [PDF]

The Open Conference Proceedings Journal, 2013
Mohamad Firdhaus Ramli, Norashikin Saim, Rohaya Ahmad   +2 more
openaire   +1 more source

Micropropagation and production of eurycomanone, 9-methoxycanthin-6-one and canthin-6-one in roots of Eurycoma longifolia plantlets

African Journal of Biotechnology, 2012
Eurycoma longifolia or Tongkat Ali is a well known medicinal plant in Malaysia. The plants are used as main portion in herbal preparation, and have been extensively harvested. Generally, most of the raw materials required by the industries are heavily collected from the natural forests, thereby resulting in the uncontrolled exploitation of the plant ...
openaire   +1 more source

Stimulatory effect of eurycomanone from Eurycoma longifolia Jack roots on dopamine secretion in human neuroblastoma SH-SY5Y cell line

Natural Product Research
Eurycomanone has been identified as the major bioactive compound contributing to Eurycoma longifolia (EL) aphrodisiac activity, however, its mechanism of action remains obscured. Presently, eurycomanone was isolated from EL root extract and its molecular structure was identified.
Jing-Jie Ang, Naveen Kumar Hawala Shivashekaregowda, Hui-Yin Yow, Farzana Rizwan, Pooi-Fong Wong, Ibrahim Jantan, Maizatul Hasyima Omar, Norazlan Mohmad Misnan, Bin-Seng Low   +8 more
openaire   +2 more sources