Results 41 to 50 of about 1,636,757 (294)

Social Enterprise as a Model to Improve Live Release and Euthanasia Rates in Animal Shelters

Frontiers in Veterinary Science, 2021
This paper explored the role that social entrepreneurship may play in helping to improve euthanasia and live release rates in animal shelters. This paper used a qualitative, comparative ethnographic study that included semi-structured interviews ...
Jennifer Thomsen, Bastian Thomsen, Bastian Thomsen, Bastian Thomsen, Kellen Copeland, Sarah Coose, Sean Blackwell, Vitoria Dante   +7 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Mourned pets. About Coping with Animal Death in Veterinary Practice and Caregiver’s Experience

Zoophilologica, 2023
The article is written from the first-person perspective as an autoethnographical attempt to describe the experience of loss of a pet companion, a cat, when the decision about euthanasia was challenged and undermined, causing regret and complex feelings
Łucja Lange
doaj   +1 more source

Euthanasia perspectives of Spanish-speaking caretakers [PDF]

, 2021
Conducting euthanasia has been reported as a significant stressor for animal caretakers.This article is published as Yarian, J., A. Johnson, S. Millman, J. Ross, B. Skaar, K. Stalder, M. Pairis-Garcia, I. Robles, A. Arruda, and C. Jass. 2021.
Robles, Ivelisse, Millman, Suzanne, Ross, Jason, Jass, Cassandra, Skaar, Brad, Stalder, Kenneth, Johnson, Anna, Arruda, Andréia, Yarian, Jacob, Pairis-Garcia, Monique   +9 more
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Factors associated with behavioral euthanasia in pet dogs

Frontiers in Veterinary Science
When pet dogs demonstrate certain serious problem behaviors, this may lead owners to choose behavioral euthanasia. However, research on behavioral euthanasia of pet dogs is sparse and previously published papers have not specifically sampled owners who ...
Miranda Hitchcock, Miranda K. Workman, Adeline P. Guthrie, Audrey Ruple, Erica N. Feuerbacher   +4 more
doaj   +1 more source

The future of euthanasia politics in the Australian state parliaments [PDF]

, 2014
There has been significant activity on voluntary euthanasia, with bills seeking to reform the law on the practice introduced in all of the Australian state parliaments except Queensland.
Alison Plumb
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

A Comparative Study on the Effect of Euthanasia Methods and Sample Storage Conditions on RNA Yield and Quality in Porcine Tissues

Animals, 2023
Animals used in research often have to be euthanised, especially when tissue sampling is essential. Recently, a euthanasia method, utilizing an inhalant anaesthetic ‘nitrogen gas in foam’ in an anoxia box (ANOXIATM), has gained considerable interest as ...
Bimal Chakkingal Bhaskaran, Roel Meyermans, Wim Gorssen, Gregory Erich Maes, Steven Janssens, Nadine Buys   +5 more
doaj   +1 more source