Results 51 to 60 of about 1,253,381 (177)

Targeting Ninjurin‐1‐Mediated Microglial Pyroptosis Attenuates Neuroinflammation and Neuronal Injury Following Intracerebral Hemorrhage

Brain and Behavior, Volume 16, Issue 11, November 2026.
In response to intracerebral hemorrhage, NF‐κB signaling upregulates Nlrp3 and Ninjurin‐1 (Ninj1) in microglia. NLRP3 inflammasome activation triggers GSDMD pore formation, whereas Ninj1 oligomerizes to execute terminal plasma membrane rupture (PMR) and DAMP release (such as HMGB1).
Liqiang Peng, Aosheng Peng, Hui Zhu, Ting Sun, Pan Liu, Ting Qi   +5 more
wiley   +1 more source

Supplementing With the Vitamin A Metabolite Retinoic Acid Can Alleviate Negative Affective States Caused by SPI1‐Induced Immune and Metabolic Dysfunctions Following Intestinal Barrier Impairment

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Ulcerative colitis (UC) and depression (DP) are significant comorbidities in epidemiological research. However, the mechanisms underlying UC‐induced DP remain poorly understood. Myeloid differentiation and retinoic acid metabolic dysregulation are implicated in both conditions, yet their interconnection in the context of comorbidity is unclear.
Yang Feng, Pai Xie, Ni‐ren Li, Yi‐xuan Zeng, Bing‐ying Deng, Yu‐feng Gu, Si‐fan Lu, Yi Liu   +7 more
wiley   +1 more source

Clinical Psychology Today Vol 3 Issue 2 (Winter 2019) [PDF]

, 2019
'Clinical Psychology Today' a journal for Clinical Psychologists to share research, practice and exchange views on the science and practice of Clinical Psychology.
Collins, Padraig
core  

Adolescent Ethanol Exposure Disrupts the Mature Phenotype of Surviving Neuroprogenitors in Female Mice

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT Rodent models of human adolescent binge drinking persistently reduce adult neurogenesis and induce innate immune signaling cascades, suggesting long‐lasting dysfunction in the hippocampal neurogenic niche. Nevertheless, many neuroprogenitors survive, and the impact of adolescent ethanol on the mature phenotype of these surviving neurons is ...
Kaitlyn Campbell, Madison McDowell, Eymani Alston, Hunter Kelley, Michael Kasten, Paul B. Manis, Fulton Crews, Victoria Macht   +7 more
wiley   +1 more source

Identification of Potential Biomarkers for Ulcerative Colitis and Analysis of Immune Cell Infiltration: A Study Based on Data‐Independent Acquisition Proteomics and the GEO Public Database

PROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Background Ulcerative colitis (UC) is a challenging inflammatory bowel disease characterized by chronic inflammation of the colon's mucosal layer. Despite advances in medical research, UC lacks definitive diagnostic tests and targeted treatments.
Shuai Wang, Hualiang Deng, Dajuan Sun
wiley   +1 more source

Accomplishing Ethics‐Work as a Generic Social Process

Symbolic Interaction, Volume 49, Issue 4, Page 978-1002, November 2026.
Existing systems of university research ethics are often criticized by those in the qualitative research tradition. A common thread is that ethics cannot be fully anticipated before the research begins, as is expected by most institutional review boards.
Deana Simonetto, Antony Puddephatt
wiley   +1 more source

How Knowledge Becomes Credible Under Epistemic Uncertainty: A Grounded Theory of Telepathic Animal Communication Websites

Canadian Review of Sociology/Revue canadienne de sociologie, Volume 63, Issue 4, November 2026.
ABSTRACT How credibility is constructed under conditions of epistemic uncertainty is a central question in the sociology of knowledge. Telepathic animal communication (TAC) represents a field in which knowledge claims are inherently non‐verifiable, yet services are actively marketed and consumed.
Annika Barzen, Dylan Göpfert
wiley   +1 more source

Periodontitis‐Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine‐Mediated Acidosis Adaptation

Cell Proliferation, Volume 59, Issue 11, November 2026.
This study identifies a link between periodontitis and CRC progression mediated by carnosine‐enriched circulating EVs. These EVs target the intestine and elevate tumour cell intracellular pH (pHi), which rescues lysosomal function. This process drives a transition from dysfunctional lysosomes to functional ones, promoting a high malignancy phenotype in
Ruoyi Wu, Zihan Cai, Hualing Sun, Haikun Yu, Bicheng Zhang, Chi Zhang, Yi Fan, Xiaoxuan Zhu, Yueqi Ni, Yu Cui, Kaixin Wang, Zhe Li, Xinyi Zhou, Qing He, Yanru Wu, Yufeng Zhang   +15 more
wiley   +1 more source

The Experience of Care in People With Palliative Needs and Their Families: A Qualitative Metasynthesis

Journal of Clinical Nursing, Volume 35, Issue 11, Page 5099-5116, November 2026.
ABSTRACT Aim To synthesise and reinterpret qualitative evidence on how people with palliative care needs and their family caregivers experience the care process. Background Palliative care aims to provide holistic, person‐ and family‐centred care.
Ana Gil Méndez, Caterina Checa Jiménez, Ingrid Bullich Marín, Laura Navarrete Reyes, Carolina Watson Badia, Nina Granel Gimenez, Lídia Ribera Barberan, Mireia Subirana Casacuberta, Juan M. Leyva‐Moral   +8 more
wiley   +1 more source

A Case Against Dutch Euthanasia

, 1989
The growing acceptance of voluntary active euthanasia by the Dutch is examined in relation to the plastic cards requesting active euthanasia carried by many people in The Netherlands, public opinion polls, and support by leading medical figures of the ...
Fenigsen, Richard
core   +1 more source