Results 31 to 40 of about 3,381 (135)

Pyruvate Kinase M2 Upregulation Is Associated With Guillain–Barré Syndrome Risk and Immune Dysregulation: Insights From Mendelian Randomization and the Experimental Autoimmune Neuritis Model

open access: yesBrain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Objective This study aimed to investigate the potential involvement of pyruvate kinase M2 (PKM2) in the pathogenesis of Guillain–Barré syndrome (GBS). Methods Mendelian randomization (MR) analysis was used to evaluate the causal association between PKM2 expression and GBS susceptibility, with mediation analysis performed to explore immune cell‐
Shuping Liu   +5 more
wiley   +1 more source

Adenovirus Vector‐Mediated In Vivo Knock‐in Treatment of Neonatal Phenylketonuria Mice Using Terminally Cleaved Donor DNA

open access: yesThe Journal of Gene Medicine, Volume 28, Issue 8, August 2026.
We successfully developed a highly efficient knock‐in adenovirus vector, AxPah‐6g‐cut. This vector cleaves not only the genomic target site but also the terminus of the donor DNA in the vector. When this vector was intravenously administered twice to phenylketonuria (Pahenu2) mice together with a Cas9‐expressing vector, AxCBCas9, it resulted in the ...
Megumi Yamaji   +10 more
wiley   +1 more source

Expectations of dog and cat owners when dealing with veterinary errors and the emotional impact of such errors

open access: yesVeterinary Record, Volume 199, Issue 3, Page e106-e114, 1/8 August 2026.
Abstract Background This study explored dog and cat owners' experiences of veterinary medical errors and their emotional impact, hypothesising that such errors impose a significant emotional burden. Methods German‐speaking dog and cat owners who may have encountered a veterinary medical error were recruited via social media platforms and questioned ...
Vivian K. Johann   +3 more
wiley   +1 more source

A systematic review of autism in the workplace: Taking a holistic perspective on the Autistic employee life cycle

open access: yesApplied Psychology, Volume 75, Issue 4, August 2026.
Abstract Extant research on autism at work remains scattered across areas of study, including organizational psychology, disability studies, and management, suggesting the need to systematically organize the body of knowledge. In this systematic review, I explore the small, yet growing body of literature focused on autism at work and integrate research
Michelle Blood Checketts
wiley   +1 more source

Contextualizing personality–job performance relationships: A cultural tightness–looseness‐based meta‐analysis

open access: yesApplied Psychology, Volume 75, Issue 4, August 2026.
Abstract Cultural tightness–looseness (CTL), commonly studied in the cross‐cultural psychology literature, has been proposed as a distal (i.e., country‐level) operationalization of situational strength, with tight and loose countries representing strong and weak country‐level situations, respectively.
JeongJin Kim   +7 more
wiley   +1 more source

Aerobic Endurance Training Modulates Cardiac Renin‐Angiotensin System Peptides and Matrix Metalloproteinase Activity During Chronic Stress

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT To investigate the involvement of metalloproteinases (MMPs) in the context of endurance training and their interactions with renin‐angiotensin signalling (RAS) in stress‐induced pathophysiological responses. Trained rats were submitted to 8‐weeks of endurance treadmill training with chronic mild stress (CMS), TS rats, and without CMS (T).
Vinicius Guzzoni   +14 more
wiley   +1 more source

Suffering, Silence, and the State: Mass Observation's 1994 Assisted Dying Letters and the Enduring Politics of Palliative Care

open access: yesPolitics &Policy, Volume 54, Issue 4, August 2026.
ABSTRACT Assisted dying has returned to UK policy debate amid legislative scrutiny and growing hospice sector instability. This paper brings 1994 Mass Observation data into dialog with contemporary debates to examine how members of the public understood suffering, autonomy, and care at the end of life.
Kathryn McEwan   +2 more
wiley   +1 more source

Additional file 1: of Attitudes towards assisted suicide and euthanasia among care-dependent older adults (50+) in Austria: the role of socio-demographics, religiosity, physical illness, psychological distress, and social isolation

open access: yes, 2017
This manuscript is linked to an additional file (additional_file1), a MS-Word data-file containing two tables (Additional Table S1 and S2) showing the results of bivariate associations between predictor and outcome variables. (DOCX 20 kb)
Stolz, Erwin   +3 more
openaire   +1 more source

Euthanasia in India: A Legal, Socio-Cultural, and Psychological Analysis of the Right to Die with Dignity

open access: yesInternational Journal for Research in Applied Science and Engineering Technology
Euthanasia remains one of the most complex issues in contemporary legal and ethical discourse, particularly in a diverse society such as India, where law, religion, culture, and family values are deeply intertwined. This research examines euthanasia in India through a multidimensional framework by analysing its legal evolution, socio-cultural ...
openaire   +1 more source

How Do Individuals View Euthanasia In Different Cultural Backgrounds Based on Different Ideas of Moral Psychology

open access: yesJournal of Education, Humanities and Social Sciences
To this day, euthanasia remains a topic of lively discussion. The debate over whether it should be practiced or not never stops. This paper presents basic information about euthanasia and analyzes different people's views on euthanasia in the context of religious beliefs and philosophical ideas based on moral psychology. People who grow up in different
openaire   +1 more source

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