Results 91 to 100 of about 105,097 (295)
Agent-Based Emergency Evacuation Simulation with Individuals with Disabilities in the Population [PDF]
Catastrophic events have raised numerous issues concerning how effectively the built environment accommodates the evacuation needs of individuals with disabilities.
Keith Christensen, Yuya Sasaki
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FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Agent-Based Evacuation Modeling: Enhancing Building Safety in Emergency Scenarios
Smart CitiesBuildings and their supporting infrastructure are vulnerable to both natural and human-made disasters, which pose significant risks to the safety of the occupants.
Miguel Islas-Toski +3 more
doaj +1 more source
Applied Artificial Bee Colony Optimization Algorithm in Fire Evacuation Routing System
Journal of Applied Mathematics, 2018 Every minute counts in an event of fire evacuation where evacuees need to make immediate routing decisions in a condition of low visibility, low environmental familiarity, and high anxiety.
Chen Wang +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
People Movement Characteristics Based on an Evacuation Test
Communications, 2014 Modelling of the evacuation of people is the only method leading to a proper design of emergency escape routes from buildings. The background details necessary for modelling can only be obtained from actual incidents or evacuation tests.
Martin Lopusniak, Dusan Katunsky
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
The verification of wildland-urban interface fire evacuation models. [PDF]
Nat Hazards (Dordr), 2023 Ronchi E +11 more
europepmc +1 more source
Agent Street: An Environment for Exploring Agent-Based Models in Second Life [PDF]
Urban models can be seen on a continuum between iconic and symbolic. Generally speaking, iconic models are physical versions of the real world at some scaled down representation, while symbolic models represent the system in terms of the way they ...
Andrew Crooks +2 more
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