Results 211 to 220 of about 17,544,570 (361)
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
World's First Artificial Intelligence-Based Evaluation of Rist Catheter Stability in Transradial Procedures: A Feasibility Study. [PDF]
J Neuroendovasc TherTanoue S, Sakakura Y, Kono K.
europepmc +1 more source
Evaluation in the Psychological Help: Psychological Group Counseling Experience from Members' Eyes
Taşkın Yildirim +2 more
openalex +2 more sources
Report on the Establishment of CGIAR Independent Evaluation Arrangement [PDF]
, 2015 CGIAR Independent Evaluation Arrangement
core
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
How the natural environment affects psychological recovery: A case study in Changsha, China. [PDF]
PLoS OneZhao K, Zhang S, Zhao F.
europepmc +1 more source
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Molecular Oncology, EarlyView.Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source