Results 241 to 250 of about 17,544,570 (361)

IEA Inception Report: Annexes [PDF]

, 2015
CGIAR Independent Evaluation Arrangement
core  

The emerging economic evidence and methods used to evaluate clinical registries: a systematic scoping review protocol. [PDF]

BMJ Open
Pisavadia K, Hartfiel N, Varghese L, Krayer A, Hobson G, Masters R, Poole R, Robinson C, Edwards RT, Bebbington E.   +9 more
europepmc   +1 more source

Evaluation of Changing Concepts in General Anesthesia as They Apply to Office Administration for Oral Surgery.*

, 1951
Maurice J. Oringer
openalex   +1 more source

IEA Comments on the second draft on the Options for CGIAR Governing Structures and Decision-Making [PDF]

, 2015
CGIAR Independent Evaluation Arrangement
core  

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

IEA 2014 Activity Report, Budget and Survey Results [PDF]

, 2015
CGIAR Independent Evaluation Arrangement
core  

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Automated facial feature evaluation system to prevent stress of head fixed mice. [PDF]

PLoS One
Nasr A, Rettinger G, Mansvelder HD, Sachdev RNS, Larkum ME.   +4 more
europepmc   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Bias in student evaluations of teaching in undergraduate medical education: a qualitative study from a medical school in Northern China. [PDF]

BMC Med Educ
Li Y, Sun C, Wang Y, Chi H, Tang H, Ma M, Wei L, Zhong L, Li J, Wei K, Sha Z, Fan C, Zhang G, Sun P, Jiao M.   +14 more
europepmc   +1 more source