Results 271 to 280 of about 18,898,156 (333)

A hierarchical framework to evaluate the usability of smartphone health applications. [PDF]

Sci Rep
Siddique A, Sajjad Q, Algamdi SA, Shahzad B, Hussien JM.   +4 more
europepmc   +1 more source

Decoding disparities: evaluating automatic speech recognition system performance in transcribing Black and White patient verbal communication with nurses in home healthcare

Maryam Zolnoori, Sasha Vergez, Zidu Xu, Elyas Esmaeili, Ali Zolnour, Krystal Anne Briggs, Jihye Kim Scroggins, Seyed Farid Hosseini Ebrahimabad, James M. Noble, Maxim Topaz, Suzanne Bakken, Kathryn H. Bowles, Ian Spens, Nicole Onorato, Sridevi Sridharan, Margaret V. McDonald   +15 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Effect on bone mineralization of continued growth hormone therapy at the transition between childhood and adulthood. [PDF]

Endocr Connect
Bailly C, Le Roux E, Polak M, Touraine P.   +3 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

An ESTRO-EPTN Delphi consensus on robustness evaluation in proton therapy. [PDF]

Phys Imaging Radiat Oncol
Fracchiolla F, Meijers A, Orlandi E, Korevaar E, Whitfield G, Jensen K, Hoogeman M, Wijsman R, Jouglar E, Weerd EV, Pérez JM, Rinaldi I, Garbacz-Stryszewska M, Cianchetti M, Feijoo MM, Molinelli S, Elstrøm UV, Pica A, Gosling A, Koczur B, Dahlgren CV, Alterio D, Dale E, Farid G, Compter I, Doyen J, Dale JE, Färlin J, Urbanek K, Fjæra LF, Lambrecht M, Ugland M, Tschiche M, Vidal M, Lowe M, Bütof R, Gulliford S, Comi S, Habraken S, Tessonnier T, Sterpin E, Widesott L.   +41 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Best practices in methodological frameworks for evaluating procedure-based treatments in traditional, complementary and integrative medicine: a scoping review protocol. [PDF]

BMJ Open
Liu Y, Cui S, Zhang Y, Song Z, Luo Z, Chen Z, Gao Q, Wang J.   +7 more
europepmc   +1 more source

A Novel Point of Common Coupling Direct Power Control Method for Grid Integration of Renewable Energy Sources: Performance Evaluation among Power Quality Phenomena

Yusuf Al‐Turki, Abdullah Ali Alhussainy, Sultan Alghamdi, Muhyaddin Rawa   +3 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source