Results 51 to 60 of about 17,544,570 (361)

Analytical Characterization for Similarity Assessment Between an Aflibercept Biosimilar SB15 and Reference Product (Eylea®)

open access: yesOphthalmology and Therapy
Introduction SB15 is a proposed biosimilar product of reference aflibercept (Eylea®), an approved biological drug product for retinal diseases including neovascular age-related macular degeneration (nAMD).
Hangyeore Lee   +7 more
doaj   +1 more source

Comparison of commonly used ICR stocks and the characterization of Korl:ICR

open access: yesLaboratory Animal Research, 2017
Mouse is a commonly used animal in life science studies and is classified as outbred if genetically diverse and inbred if genetically homogeneous. Outbred mouse stocks, are used in toxicology, oncology, infection and pharmacology research.
Hye-Jun Shin   +7 more
doaj   +1 more source

Evaluation of Evaluation [PDF]

open access: yesBehaviormetrika, 1974
It was proposed that people could evaluate the other person’s evaluation scheme in terms of the similarity (or dissimilarity) of the other person’s evaluation scheme to their own schemes. The metric for the dissimilarity of evaluation schemes was proposed to be the Minkowski-p metric for the utilities evaluated under different schemes.
openaire   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

The Adverse Drug Reactions Registered During the Postmarketing Period

open access: yesБезопасность и риск фармакотерапии, 2019
Efficacy, safety and biotransformation features of any drug are fully revealed during widely using. Therefore, postmarketing studies of the pharmacological properties of drugs are an integral component of pharmacovigilance.
E. V. Shubnikova   +8 more
doaj   +1 more source

mRNA-1273 bivalent (original and Omicron) COVID-19 vaccine effectiveness against COVID-19 outcomes in the United States

open access: yesNature Communications, 2023
The bivalent (original and Omicron BA.4/BA.5) mRNA-1273 COVID-19 vaccine was authorized to offer broader protection against COVID-19. We conducted a matched cohort study to evaluate the effectiveness of the bivalent vaccine in preventing hospitalization ...
Hung Fu Tseng   +17 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

POST-MARKETING DRUG SAFETY RESEARCH: ANALYSIS OF RECOMMENDATIONS OF FOREIGN REGULATORS

open access: yesБезопасность и риск фармакотерапии, 2018
The monitoring of information on the safety of various drugs is becoming more relevant day by day, as the number of drugs on the  pharmaceutical market increases, generic drugs, bio-analogous drugs appear.
E. V. Shubnikova   +8 more
doaj   +1 more source

Evaluation methodologies in Automatic Question Generation 2013-2018 [PDF]

open access: yes, 2018
In the last few years Automatic Question Generation (AQG) has attracted increasing interest. In this paper we survey the evaluation methodologies used in AQG.
Amidei, Jacopo   +2 more
core   +1 more source

Using mHealth to improve health care delivery in India: A qualitative examination of the perspectives of community health workers and beneficiaries. [PDF]

open access: yes, 2020
BACKGROUND:mHealth technologies are proliferating globally to address quality and timeliness of health care delivery by Community Health Workers (CHWs). This study aimed to examine CHW and beneficiaries' perceptions of a new mHealth intervention (Common ...
Buback, Laura   +5 more
core   +2 more sources

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