Results 201 to 210 of about 1,812,452 (266)

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

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Criteria for concept evaluation

Journal of Advanced Nursing, 1996
One of the roles of qualitative enquiry is the utilization of qualitative methods for the development, refinement or modification of concepts Yet, to date, there are no criteria for evaluating the adequacy of a concept In this paper, the anatomy of a concept is presented, methods of concept analysis critiqued, and criteria for evaluation of the level ...
J M, Morse, C, Mitcham, J E, Hupcey, M C, Tasón   +3 more
openaire   +2 more sources

Criteria for Evaluating Psychotherapy

Archives of General Psychiatry, 1978
• The efficacy of psychotherapy and the relative efficacy of different therapies are important issues that continue to receive attention in the literature. Questions about the efficacy of treatment usually are addressed by comparing groups that receive different treatment (or control) conditions.
A E, Kazdin, G T, Wilson
openaire   +2 more sources

Security evaluation criteria

Computers & Security, 1994
This article is a position paper on security evaluation criteria. The paper is prepared by Jaap den Engelsman, Martin de Graaf, Paul Overbeek, Hans Schoone en Leon Strous, members of working group SB.W06 Security Evaluation Criteria of the Special Interest Group on Information Security (SIGIS) of the Dutch Computer Society (NGI).
openaire   +1 more source

Criteria For Evaluating Usability Evaluation Methods

International Journal of Human-Computer Interaction, 2001
The current variety of alternative approaches to usability evaluation methods (UEMs) designed to assess and improve usability in software systems is offset by a general lack of understanding of the capabilities and limitations of each. Practitioners need to know which methods are more effective and in what ways and for what purposes.
H. Rex Hartson, Terence S. Andre, Robert C. Williges   +2 more
openaire   +1 more source

Criteria for Evaluation of Theory

Nursing Science Quarterly, 2005
This column presents criteria for evaluation of nursing theories specified by Jacqueline Fawcett and Rosemarie Rizzo Parse. Fawcett’s criteria are significance, internal consistency, parsimony, testability, empirical adequacy, and pragmatic adequacy.
openaire   +2 more sources