Results 81 to 90 of about 6,199,232 (247)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Gradgrinding the Social Sciences: The Politics of Metrics of Political Science [PDF]

open access: yes, 2009
Copyright @ 2009 The AuthorThis article employs an interpretive approach, and in the light of contributions to this symposium by Butler and McAllister, and McLean et al., holds that metrics of research ‘quality’ are socially constructed and hence are as ‘
Donovan, C   +2 more
core   +1 more source

A proposal for the evaluation of adaptive information retrieval systems using simulated interaction [PDF]

open access: yes, 2010
The Centre for Next Generation Localisation (CNGL) is involved in building interactive adaptive systems which combine Information Retrieval (IR), Adaptive Hypermedia (AH) and adaptive web techniques and technologies.
Lawless, Séamus   +3 more
core   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

An empirical study of package coupling in Java open-source [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Excessive coupling between object-oriented classes in systems is generally acknowledged as harmful and is recognised as a maintenance problem that can ...
Mubarak, Asma
core   +3 more sources

Determinants of effective vaccine coverage in low and middle-income countries: a systematic review and interpretive synthesis

open access: yesBMC Health Services Research, 2017
Background Many children in low and middle-income countries remain unvaccinated, and vaccines do not always produce immunity. Extensive research has sought to understand why, but most studies have been limited in breadth and depth.
David E. Phillips   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Annual corporate evaluation report 2000 [PDF]

open access: yes, 2000
French version available in IDRC Digital Library: Rapport annuel sur l'évaluation 2000The Annual Corporate Evaluation (ACE) Report is an element of the Centre's performance monitoring and reporting system.
IDRC. Evaluation Unit
core  

A burden of proof study of the effects of exposure to high fasting plasma glucose on the risk of seven types of cancer

open access: yesScientific Reports
Cancer is a major public health problem strongly influenced by genetic factors and aging; however, a proportion of its burden can be attributed to potentially modifiable risk factors.
Paula Portal Teixeira   +14 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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