Results 41 to 50 of about 2,025,466 (207)

A Broad Evaluation of the Tor English Content Ecosystem

open access: yes, 2019
Tor is among most well-known dark net in the world. It has noble uses, including as a platform for free speech and information dissemination under the guise of true anonymity, but may be culturally better known as a conduit for criminal activity and as a
Allahyari, Mehdi   +3 more
core   +1 more source

Entities as topic labels : combining entity linking and labeled LDA to improve topic interpretability and evaluability [PDF]

open access: yes, 2016
Digital humanities scholars strongly need a corpus exploration method that provides topics easier to interpret than standard LDA topic models. To move towards this goal, here we propose a combination of two techniques, called Entity Linking and Labeled
Lauscher, Anne   +3 more
core   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Post-Occupancy Evaluation for Adaptive Façades

open access: yesJournal of Facade Design and Engineering, 2018
Post-occupancy evaluation is a valuable method of generating information on the performance of adaptive building façades in relation to users. This evaluation technique involves both procedural methods, such as soft-landing, and empirical measuring ...
Shady Attia   +5 more
doaj   +1 more source

Early Exposure to and Preparation for College: A Guide for Educators [PDF]

open access: yes, 2016
Since 2012, the NYC Department of Education's Expanded Success Initiative (ESI) has provided funding and professional development to 40 City high schools with the goal of helping them develop new strategies (or expand existing efforts) aimed at ...
Adriana Villavicencio, Tony Laing
core  

Statistical Significance Testing in Information Retrieval: An Empirical Analysis of Type I, Type II and Type III Errors

open access: yes, 2019
Statistical significance testing is widely accepted as a means to assess how well a difference in effectiveness reflects an actual difference between systems, as opposed to random noise because of the selection of topics.
Hanjalic, Alan   +2 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Evaluation of Health Action Process Approach in Explaining Healthy Diet among the Patients with Type 2 Diabetes

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives: Over the last two decades, the prevalence of type2 diabetes (T2DM) has more than doubled worldwide. Researches have shown that with changes in lifestyle, especially diet, the incidence of complications of diabetes could be ...
Hossein Rohani   +4 more
doaj  

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