Results 51 to 60 of about 99,581 (308)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Value Disagreement and Two Aspects of Meaning [PDF]

open access: yes, 2017
The problem of value disagreement and contextualist, relativist and metalinguistic attempts of solving it are laid out. Although the metalinguistic account seems to be on the right track, it is argued that it does not sufficiently explain why and how ...
Rast, Erich
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Crowdsourcing a Word-Emotion Association Lexicon [PDF]

open access: yes, 2012
Even though considerable attention has been given to the polarity of words (positive and negative) and the creation of large polarity lexicons, research in emotion analysis has had to rely on limited and small emotion lexicons.
Mohammad, Saif M., Turney, Peter D.
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Thick Concepts [PDF]

open access: yes, 2016
A term expresses a thick concept if it expresses a specific evaluative concept that is also substantially descriptive. It is a matter of debate how this rough account should be unpacked, but examples can help to convey the basic idea.
Kyle, Brent G.
core  

Suffering Pains [PDF]

open access: yes, 2019
The paper aims at clarifying the distinctions and relations between pain and suffering. Three negative theses are defended: 1. Pain and suffering are not identical. 2.
Massin, Olivier
core   +1 more source

A Moral Judgment System using Evaluation Expressions

open access: yesTransactions of Japan Society of Kansei Engineering, 2014
In this paper, we propose a moral judgment system. Moral judgment means right and wrong judgment. The proposed system consists of the learning phase and the moral judgment phase. In the learning phase, the positive words and the negative words (evaluation expressions) are extracted based on the cooccurrence frequency of the learning data and the words ...
Masahiro Yamamoto, Masafumi Hagiwara
openaire   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

THE OPERATIONAL COMPONENT AND THE FORMATION OF A HISTORICAL CULTURE [PDF]

open access: yesVarela, 2018
The formation of a historical culture is a process by which the conscious appropriation of a conception allows to operate in the cognitive, attitudinal and evaluative areas is produced, illustrating in its context ...
Lainy Rodríguez Hurtado   +2 more
doaj  

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