Results 181 to 190 of about 303,442 (283)

Antenatal diagnosis and maternal sirolimus treatment of polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Background Polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome is a rare autosomal recessive mTORopathy caused by biallelic STE20‐related kinase adaptor alpha (STRADA) loss‐of‐function variants. Animal models demonstrate that in utero mechanistic target of rapamycin (mTOR) inhibition can prevent cortical dyslamination ...
Christian Macedonia   +5 more
wiley   +1 more source

Comparative Anatomy of the Hyoid Apparatus in Various Dog Breeds: Insights From Clinical Imaging

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study identifies breed‐related shape differences in the canine hyoid apparatus using geometric morphometrics. The results suggest that skull type influences hyoid morphology, with potential functional implications for swallowing, vocalisation and tongue movement.
Yusuf Altundağ   +6 more
wiley   +1 more source

Successful Management of Septic Splenitis in an Abyssinian Cat

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho   +10 more
wiley   +1 more source

The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age‐Dependent Structural Deficits in the Kidney

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
During kidney aging, loss of the MICOS complex drives cristae disorganization, impairs oxidative capacity, and alters mitochondrial dynamics. MICOS disruption elevates mitochondrial ROS and disrupts calcium homeostasis, linking mitochondrial structural remodeling to metabolic dysfunction in aging kidney tissue.
Prasanna Katti   +48 more
wiley   +1 more source

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