Results 51 to 60 of about 964,727 (298)
In this note, we begin by reviewing an argument (independent from 1304.6483) that the large AdS black holes dual to typical high-energy pure states of a single holographic CFT must have some structure at the horizon (i.e. a firewall/fuzzball). By weakly coupling the CFT to an auxiliary system, such a black hole can be made to evaporate. In a case where
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A semi-analytical model of disk evaporation by thermal conduction [PDF]
The conditions for disk evaporation by electron thermal conduction are examined, using a simplified semi--analytical 1-D model. The model is based on the mechanism proposed by Meyer & Meyer-Hofmeister (1994) in which an advection dominated accretion flow
Dullemond, C. P.
core +2 more sources
The Effect of Salinity on Water Evaporation and the Associated Determinants
【Objective】 Water evaporation is influenced by many factors, besides meteorological factors, salinity also has an important effect on it. The aim of this paper is to study its impact on water evaporation in coastal saline-alkali land.
CHEN Huanyu +9 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Calculation of evaporative heat loss is essential to heat balance calculations. Despite recognition that the value for latent heat of evaporation, used in these calculations, may not always reflect the real cooling benefit to the body, only limited quantitative data on this is available, which has found little use in recent literature.
Havenith, G. +8 more
openaire +4 more sources
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Bacterial Extracellular Polymeric Substances Amplify Water Content Variability at the Pore Scale
The function of microbial communities in soil is inextricably linked with the complex physical, chemical, and biological structure of the soil itself.
Yi-Syuan Guo +8 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

