Results 61 to 70 of about 459,172 (301)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Evaporating firewalls [PDF]

open access: yesJournal of High Energy Physics, 2014
In this note, we begin by reviewing an argument (independent from 1304.6483) that the large AdS black holes dual to typical high-energy pure states of a single holographic CFT must have some structure at the horizon (i.e. a firewall/fuzzball). By weakly coupling the CFT to an auxiliary system, such a black hole can be made to evaporate. In a case where
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Testing Iron Stable Isotope Ratios as a Signature of Biomass Burning

open access: yesAtmosphere, 2019
Biomass burning is an important source of soluble Fe transported to the open ocean; however, its exact contribution remains unclear. Iron isotope ratios can be used as a tracer because Fe emitted by combustion can yield very low Fe isotope ratios due to ...
Minako Kurisu, Yoshio Takahashi
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Micro-Explosion Phenomenon: Conditions and Benefits

open access: yesEnergies, 2022
Adding water to fuel droplets is known to lead to puffing and micro-explosion. Puffing and micro-explosion lead to a rapid increase in the liquid fuel surface area.
Dmitrii V. Antonov   +2 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Effect of Pore Characteristics in Polyvinylidene Fluoride/Fumed Silica Membranes on Mass Flux in Solar-Assisted Evaporation Applications

open access: yesApplied Sciences, 2019
Although important, very little has been demonstrated in the literature to experimentally demonstrate the effects of porosities and pore size on the evaporation flux in polymeric membranes. Additionally, we suspect that a batch-mode setup, i.e., stagnant
Mona Bahman   +3 more
doaj   +1 more source

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