Results 71 to 80 of about 6,674,346 (214)
Ophthalmology and Therapy, 2023 Introduction To evaluate the efficacy and safety of Quantum Molecular Resonance (QMR) treatment in patients with severe dry eye disease (DED), as well as its effects on aqueous-deficient (ADDE), evaporative (EDE), and mixed (MDE) dry eye. Methods In this
Antonio Ballesteros-Sánchez +7 more
doaj +1 more source
How Can We Best Diagnose Severity Levels of Dry Eye Disease: Current Perspectives [Corrigendum]
, 2023 Chester T, Garg S, Johnston J, Ayers B, Gupta P. Clin Ophthalmol. 2023;17:1587–1604. Page 1587, author list, the text “Brandon Ayers” should read “Brandon Ayres”.
Ayers B +4 more
core
Advanced Science, EarlyView.An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Ziheng Wang +15 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyDry eye disease is a multifactorial, heterogeneous ocular surface disorder characterized primarily by an imbalance in tear film homeostasis. The traditional classification into “aqueous deficiency” and “evaporative” types fails to fully account for the ...
Zhizi Zhang +9 more
doaj +1 more source
Advanced Science, EarlyView.BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai +7 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree +18 more
wiley +1 more source
Treatment of Ocular Pain Not Responsive to Traditional Dry Eye Disease Treatments
, 2023 Neuropathic ocular pain (NOP) in dry eye disease can be a challenging condition to treat. The pathogenesis of NOP often results from injury to the corneal nerves, leading to neural plasticity and peripheral and central neuronal sensitization.
Kuruvilla, Merin +5 more
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Advanced Science, EarlyView.A mechanically robust, self‐healable, moisturizing, cryotolerant and adhesive GelMA hydrogel is developed by incorporating polyvinyl alcohol, acrylic acid, sodium tetraborate, and glycerol into GelMA matrix via a photoinitiated polymerization process. The hydrogel‐derived omni‐healable ionotronic pressure sensor can sensitively and consistently monitor
Zhikang Li +16 more
wiley +1 more source
Dry eye disease is recognised to be a highly heterogeneous and multifactorial condition with a myriad of etiological drivers [1–3], and subtype classification evaluation is therefore critical for guiding tailored management strategies for individual ...
Power, Barry +3 more
core +1 more source
Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease
Advanced Science, EarlyView.A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li +9 more
wiley +1 more source