Results 81 to 90 of about 6,674,346 (214)

Meibomian gland dysfunction in Sjögren's disease

Frontiers in Medicine
For many years, lacrimal gland dysfunction was considered the primary cause of dry eye disease in Sjögren's Disease (SjD). However, recent studies reveal that meibomian gland dysfunction (MGD) is also a significant contributor in dry eye associated with ...
Esther N. Anuwa-Amarh, Jillian F. Ziemanski   +1 more
doaj   +1 more source

Real‐Time Monitoring of Mass and Mechanical Properties in Single Cells and Multicellular Spheroids

Advanced Science, EarlyView.
This study introduces photothermally actuated microcantilevers combined with optical microscopy to simultaneously measure morphology, mass, and mechanical properties of cellular systems in real‐time. The findings link cytoplasm‐dominated mechanical energy dissipation to the Q‐factor as a novel biophysical parameter.
Ilaria Incaviglia, Giulia E. M. Ammirati, Sophie Herzog, Tommy Krug, Nico Strohmeyer, Miguel Camacho Rufino, Matthias P. Lutolf, David A. Weitz, Daniel J. Müller   +8 more
wiley   +1 more source

Understanding the true burden of dry eye disease

, 2015
The term 'dry eye' (DE) has evolved over the past two decades to include both symptoms (visual complaints and dysesthesias) and signs (aqueous and evaporative deficiency) of disease.
Felix, Elizabeth R, Galor, Anat, Levitt, Roy C, Sarantopoulos, Constantine D   +3 more
core   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

Advanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin, Sisi Chen, Shengli Huang, Mengqi Huang, Jingyan Zhu, Zijian Wang, Jianliang Shen, Qinxiang Zheng   +7 more
wiley   +1 more source

Agronomic and Nutritional Perspectives on Vegetable Crops in Africa

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Vegetable production plays a key role in food security, nutrition, and livelihoods across Africa. Moreover, African indigenous vegetables emerge as underutilized yet highly valuable crops, rich in macro‐ and micronutrients, as well as bioactive compounds with an array of health benefits.
Đorđe Vojnović, Pamela Owusu Osei, Sina Siavash Moghaddam, Issiake Konate, Jelena Popović‐Đorđević   +4 more
wiley   +1 more source

Beyond Protein Synthesis: The Multifunctional Role of Functional Amino Acids in Modulating Meat Quality in Ruminants

Animal Research and One Health, EarlyView.
Multifunctional roles of functional amino acids in regulating meat quality in ruminants: Functional amino acids (FAAs) regulate ruminant meat quality through multiple interconnected mechanisms, including antioxidant protection, metabolic regulation, signal transduction, structural support, and gene expression modulation.
Zixin Liu, Tian Xia, Xiaokang Lv, Man Ren, Chuanshe Zhou, Zhiliang Tan   +5 more
wiley   +1 more source

Surgery for the Dry Eye : Scientific Evidence and Guidelines for the Clinical Management of Dry Eye Associated Ocular Surface Disease /

, 2008
All adnexal structures - the tear system, the lids and the orbit as well as neuronal and cellular components of the ocular surface itself, i.e. the cornea and conjunctiva - are involved in tear production and maintenance.
Geerling, G.
core  

Thermal Pulsation Therapy (Lipiflow®): A Retrospective Analysis of Its Impact on Meibomian Gland Dysfunction and Dry Eye Disease

Objectives: The study aimed to evaluate the short-term effects of thermal pulsation therapy on dry eye parameters and meibomian gland dysfunction (MGD) in patients with evaporative dry eye.
Elibol, Emine, Haciagaoglu, Sezer, Emine Savran Elibol, Elibol, Emine Savran, Elibol ES, ES, Elibol, SEZER HACIAGAOGLU, Haciagaoglu S.   +7 more
core   +1 more source

AI‐enabled biomimetic flexible pressure sensors for high‐precision gait monitoring and rehabilitation assessment

FlexMat, EarlyView.
A biomimetic multilayer capacitive sensor‐integrated insole enables high‐resolution plantar pressure mapping for intelligent gait analysis. Featuring ultrahigh sensitivity, wide detection range, and long‐term stability, the system leverages AI algorithms to decode spatiotemporal pressure signals, achieving accurate recognition of postoperative ...
Yingchun Li, Yarong Ding, Kaixin Lei, Yuze Zhang, Zhenhua Lin, Jiachun Sun, Kaitai Guo, Yang Zheng, Shaozhe Tan, Xuesi Zhang, Xinyue Li, Yue Hao, Xiangning Li, Yannan Liu, Jingjing Chang   +14 more
wiley   +1 more source