Results 191 to 200 of about 305,125 (284)

Atmospherically deposited elemental mercury drives evasion of mercury from the ocean and freshwaters. [PDF]

Natl Sci Rev
Fu X, Zhang H, Tang K, Sommar J, Huang JH, Song Z, Zhang Y, Driscoll CT, Feng X.   +8 more
europepmc   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Tax Morale of Immigrants. [PDF]

Behav Sci (Basel)
Kushnirovich N.
europepmc   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

Molecular Characterization and Genomic Diversity of SARS-CoV-2 Spike Gene Variants Circulating in Iraq: Mutational Impact on ACE2 Affinity, RBD Immune Escape, and Viral Transmission. [PDF]

Adv Virol
Khudhair AM, Abdulsatar DM, Hatif ST, Ridha DJ, Ali MR, Ali JAAF.   +5 more
europepmc   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Monocytes and immune evasion strategies in HIV: Unraveling the intricacies. [PDF]

Medicine (Baltimore)
Obeagu EI, Obeagu GU.
europepmc   +1 more source

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Nature, 2020
K. Lawson, C. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, N. Mikolajewicz, Catherine Ross, K. Brown, Abdelrahman Abou Zid, Z. Fan, Shirley Hui, Jordan A. Krall, D. M. Simons, Chloe J. Slater, V. D. de Jesus, Lujia Tang, Richa Singh, J. Goldford, Sarah Martin, Qian Huang, E. A. Francis, Andrea Habsid, Ryan Climie, D. Tieu, Jiarun Wei, Ren Li, A. Tong, Michael Aregger, Katherine Chan, H. Han, Xiaowei Wang, P. Mero, J. Brumell, A. Finelli, L. Ailles, Gary D Bader, Gromoslaw A. Smolen, G. Kingsbury, Traver Hart, C. Kung, J. Moffat   +42 more
semanticscholar   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Asymmetric bubble-mediated gas transfer enhances global ocean CO₂ uptake. [PDF]

Nat Commun
Dong Y, Yang M, Bell TG, Marandino CA, Woolf DK.   +4 more
europepmc   +1 more source