Results 11 to 20 of about 1,155 (213)

Resentimiento fiscal. Una propuesta de mecanismo explicativo de la relación entre la edad y la moral fiscal

open access: yesRevista Internacional de Sociología, 2014
El presente artículo trata de micro-fundamentar una de las evidencias más sólidas de la literatura sobre moral fiscal, a saber, que los jóvenes tienden a manifestar una mayor tolerancia ante el fraude tributario que las personas de los demás grupos de ...
Toni Llacer
doaj   +1 more source

Evasión fiscal en impuestos subnacionales

open access: yesEnsayos Revista de Economía
Objetivo: Este trabajo tuvo como propósito presentar una metodología para estimar la evasión del impuesto sobre nóminas en las entidades federativas de México, particularmente la relacionada con la ocupación informal y sus determinantes. Metodología: El
Hilario Barcelata Chávez
doaj   +1 more source

WAREHOUSE TRANSFERS AND FISCAL FRAUD [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2015
The fraud and fiscal evasion phenomenon generate indisputable negative effects, which are felt directly on the level of fiscal receipts earnings, determining major distortions in the market’s functioning mechanism.
Stanciu Dorica
doaj  

Laboratorios de informática para mejorar el proceso de cumplimiento fiscal de Colombia

open access: yesRevista Científica, 2019
El artículo propone el uso de un laboratorio de informática forense regional para ayudar a solucionar el problema de evasión fiscal en Colombia, el cual supone problemas en cubrir las obligaciones públicas del Estado, y lleva a las personas a tener ...
Fabián Giovanni González-Robayo   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A VAR Analysis Regarding Tax Evasion and Tax Pressure in Romania [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2017
The tax burden is viewed, in both empirical and theoretical studies, as the main determinant of tax evasion and the shadow economy. There is an increasing fiscal pressure which suggest that taxpayers are affected by a stable over-burden of fiscal ...
Boștină Florin
doaj  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

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