Results 61 to 70 of about 39,975 (300)

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

A economia da sonegação: teorias e evidências empíricas The economics of tax evasion: theories and emprirical evidences

open access: yesRevista de Economia Contemporânea, 2005
Este artigo fornece uma visão geral da literatura teórica e empírica, nacional e internacional, acerca do estudo econômico da sonegação de impostos. Após apresentar uma definição da sonegação fiscal, em confronto com a elisão fiscal, e analisar a questão
Marcelo Lettieri Siqueira   +1 more
doaj   +1 more source

Tax evasion and tax avoidance in the towns of the Kingdom of Naples (XV-XVIII centuries) [PDF]

open access: yes, 2016
The phenomenon of tax fraud was rooted in the tax system of the old regime. The main reasons were: the magnitude of the number of the privileged, the negotiatory nature of fiscal relations between the Sovereign and his subjects, the decentralised ...
Bulgarelli Lukacs, Alessandra
core   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li   +9 more
wiley   +1 more source

Bienestar social e impuesto sobre la renta [PDF]

open access: yes, 1986
This paper intends to generalize the SANDMO'S model on evasion and optimal taxation (Journal of Public Economics, 1981, Vol. 16) in two directions.
Ruiz del Portal Bravo, Francisco Javier
core   +2 more sources

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang   +16 more
wiley   +1 more source

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

open access: yesAdvanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu   +6 more
wiley   +1 more source

The Predator-Prey Model of Tax Evasion: Foundations of a Dynamic Fiscal Ecology

open access: yesMathematics
Tax evasion is a dynamic process reflecting continuous interaction between taxpayers and regulatory institutions rather than a static deviation from fiscal equilibrium.
Miroslav Gombár   +2 more
doaj   +1 more source

Fortalecimiento de la capacidad fiscal de los países en desarrollo y apoyo a la lucha internacional contra la evasión fiscal [PDF]

open access: yes
Making progress on development means mobilising the financial resources developing countries already have in a fuller way. That involves, firstly, improving taxation systems and strengthening the fiscal administrations of those countries; and secondly ...
Carlos Garcimartín   +3 more
core  

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