Results 61 to 70 of about 39,374 (233)

Los documentos de constitución de sociedades offshore en las Islas Vírgenes Británicas y su traducción al español: un enfoque contrastivo basado en el derecho comparado aplicado a la traducción

open access: yesTrans
La compleja trama fiscal que se desarrolla actualmente a nivel mundial ha propiciado un interés sin precedentes por la evasión fiscal global, como refleja el Informe sobre la Evasión Fiscal Global que ha elaborado el EU Tax Observatory del Parlamento ...
María Presentación Aguilera   +1 more
doaj   +1 more source

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo   +14 more
wiley   +1 more source

Bienestar social e impuesto sobre la renta [PDF]

open access: yes, 1986
This paper intends to generalize the SANDMO'S model on evasion and optimal taxation (Journal of Public Economics, 1981, Vol. 16) in two directions.
Ruiz del Portal Bravo, Francisco Javier
core   +2 more sources

Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao   +10 more
wiley   +1 more source

Biomimetic Organic Nanozyme as Tumor Vaccines for Targeted Suppression of Ammonia‐Induced T Lymphocyte Death to Augment Breast Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The organic nanozyme IR‐IHpd, which has NIR‐PDT and POD‐like activity, is designed for continuous ROS generation. It is co‐encapsulated with CB‐839 and coated with DC membranes to simultaneously target tumors and T cells. Under NIR irradiation, immunogenic cell death is activated. Concurrently, CB‐839 suppresses ammonia‐induced T lymphocyte death (AITD)
Meng Suo   +7 more
wiley   +1 more source

Evasión tributaria vs. mecanismos de control implementados por la administración pública [PDF]

open access: yes, 2016
La evasión tributaria es considerada como un fenómeno preocupante para el Estado ecuatoriano, porque a pesar de los esfuerzos realizados por parte del Servicio de Rentas Internas en fortalecer los controles para reducir el nivel de evasión y en potenciar
Paredes, Priscilla Rossana
core  

Mechanical Stimuli‐Induced Manipulation of Malignant Behavior in Bioprinted Cancer Microtissues via PI3K/NF‐κB Activation

open access: yesAdvanced Science, EarlyView.
A mechanically tunable ECM platform is created by integrating dECM–alginate matrices with in‐bath tumor printing. The mechanically tunable ECM environment drives tumors to acquire hypoxia, mechanotransduction signaling, metastatic traits, and drug‐resistant phenotypes that collectively promote malignant transformation.
Seok‐Hyeon Lee   +8 more
wiley   +1 more source

The Predator-Prey Model of Tax Evasion: Foundations of a Dynamic Fiscal Ecology

open access: yesMathematics
Tax evasion is a dynamic process reflecting continuous interaction between taxpayers and regulatory institutions rather than a static deviation from fiscal equilibrium.
Miroslav Gombár   +2 more
doaj   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Improving VAT Compliance in Romania by Implementing a New Tool – Tax Lottery Receipts

open access: yesJournal of Economic Development, Environment and People, 2015
This paper aims to present and explain the newly implemented measure of organizing a Tax Lottery Receipts in Romania, in orderto combat tax evasion by raising awareness among consumers and make them responsible when purchasing any goods.The lottery ...
Dragos Ungureanu, Doina Dascalu
doaj  

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