Results 61 to 70 of about 39,900 (255)
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
LA EVASIÓN FISCAL COMO UN JUEGO PERDERPERDER
Economía y Sociedad, 2004 El Estado en la economía moderna no solo debe ser un Estado de Bienestar que ofrezca “algún tipo de protección a las personas que sin la ayuda del Estado puede que no sean capaces de tener una vida mínimamente aceptable según los criterios de la ...
Gerardo Jiménez Porras
doaj
TransLa compleja trama fiscal que se desarrolla actualmente a nivel mundial ha propiciado un interés sin precedentes por la evasión fiscal global, como refleja el Informe sobre la Evasión Fiscal Global que ha elaborado el EU Tax Observatory del Parlamento ...
María Presentación Aguilera +1 more
doaj +1 more source
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2019 The paper refers to important tax evasion consequences in the form of destabilization and countries’ fiscal development deteoriation. The main objective of the research is to analyse the selected determinants impact on short‑term fiscal imbalance ...
Lucia Mihóková +2 more
doaj +1 more source
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Advanced Science, EarlyView.Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Revista de Economia Contemporânea, 2005 Este artigo fornece uma visão geral da literatura teórica e empírica, nacional e internacional, acerca do estudo econômico da sonegação de impostos. Após apresentar uma definição da sonegação fiscal, em confronto com a elisão fiscal, e analisar a questão
Marcelo Lettieri Siqueira +1 more
doaj +1 more source
Advanced Science, EarlyView.A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee +6 more
wiley +1 more source
El Impacto potencial de BEPS en los sistemas fiscales. “Cláusula General Antiabuso Tributaria” [PDF]
, 2017 Treballs Finals del Grau de d'Administració i Direcció d'Empreses, Facultat d'Economia i Empresa, Universitat de Barcelona, Curs: 2016-2017 , Tutora: Maria Teresa DivíEl presente trabajo tiene por objeto exponer una de las herramientas de fiscalidad ...
López García, Andrea
core
Advanced Science, EarlyView.This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang +9 more
wiley +1 more source
Structural Insights Into Man9 Recognition by the HIV Antibody 2G12 Revealed by Paramagnetic NMR
Advanced Science, EarlyView.The HIV gp120 glycoprotein displays Man9 oligomannose structures that are recognized by the neutralizing antibody 2G12. Detailed characterization of the binding epitope in solution is important for immunogen design but remains challenging, since the signals of the terminal mannoses from the three arms of Man9 (D1, D2, and D3) cannot be distinguished in
Adrián Silva‐Díaz +7 more
wiley +1 more source