Results 101 to 110 of about 1,173,800 (295)
Advanced Science, EarlyView.SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source
AdvGuard: Fortifying Deep Neural Networks Against Optimized Adversarial Example Attack
IEEE AccessDeep neural networks (DNNs) provide excellent performance in image recognition, speech recognition, video recognition, and pattern analysis. However, they are vulnerable to adversarial example attacks.
Hyun Kwon, Jun Lee
doaj +1 more source
All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery
Advanced Science, EarlyView.Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi +15 more
wiley +1 more source
Friend-Guard Textfooler Attack on Text Classification System
IEEE AccessDeep neural networks provide good performance for image classification, text classification, speech classification, and pattern analysis. However, such neural networks are vulnerable to adversarial examples.
Hyun Kwon
doaj +1 more source
Evasion Attacks Against Bayesian Predictive Models
There is an increasing interest in analyzing the behavior of machine learning systems against adversarial attacks. However, most of the research in adversarial machine learning has focused on studying weaknesses against evasion or poisoning attacks to predictive models in classical setups, with the susceptibility of Bayesian predictive models to ...
Arce, Pablo G. +2 more
openaire +2 more sources
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
IEEE AccessAlthough deepfake detection methodologies have advanced considerably, they remain susceptible to evasion techniques, a critical vulnerability in forensic systems.
Yuyang Sun +2 more
doaj +1 more source
Advanced Science, EarlyView.A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo +14 more
wiley +1 more source
Adversarial Examples for CNN-Based Malware Detectors
IEEE Access, 2019 The convolutional neural network (CNN)-based models have achieved tremendous breakthroughs in many end-to-end applications, such as image identification, text classification, and speech recognition.
Bingcai Chen +4 more
doaj +1 more source
Advanced Science, EarlyView.The nanohybrid hydrogel (Fe‐BOS@C/H Gel) is composed of Fe‐Bi2O2‐XS (Fe‐BOS) photocatalysts and CS‐ADH/OHA (C/H) hydrogel. Fe‐BOS photocatalysts achieve near‐infrared (NIR) light‐driven antibacterial photocatalytic/mild photothermal therapy (APCT/MPTT), effectively eliminating methicillin‐resistant Staphylococcus aureus (MRSA) biofilms. The degradation
Dong Mo +13 more
wiley +1 more source