Results 191 to 200 of about 630,004 (299)

JUN-ENPP1-cGAS-STING axis mediates immune evasion and tumor progression in bladder cancer. [PDF]

J Transl Med
You C, Fang Q, Qing L, Xiao X, Liu Y, Yang W, Li Q, Li R, Wang Y, Dong Z.   +9 more
europepmc   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

A Critical Role of DC-SIGN⁺ Tumor-Associated Macrophages in Colorectal Cancer Immune Evasion and Progression via BCL-3-Mediated PD-L1 Expression. [PDF]

Immunotargets Ther
Zhang J, Zhao Y, Wang X, Miao C, Xu W, Wan C, Hu B, Qian F.   +7 more
europepmc   +1 more source

Tax Evasion and Ethics: A Demographic Study of 33 Countries

, 2006
Robert W. McGee, Michael Tyler
openalex   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Unveiling the ITGβ1-CLIC1 axis: a new frontier in oral squamous cell carcinoma progression and immune evasion: insights from the tumor-mimetic ECM system. [PDF]

BMC Cancer
He Y, Shuai R, Wu J, Zhou L.
europepmc   +1 more source

The Ethics of Tax Evasion: An Empirical Study of Ecuador

, 2007
Robert W. McGee, Silvia López Paláu, Fabiola Jarrín Jaramillo   +2 more
openalex   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

The influence of ferroptosis-associated gene HSPA5 on the prognosis and immune evasion of lung adenocarcinoma. [PDF]

Discov Oncol
Xiong L, Gao X, Wang L, Luo L, Su J, Wang Y, Shen Y.   +6 more
europepmc   +1 more source

SLPI⁺ AT2‐Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche

Advanced Science, EarlyView.
Integrating spatial transcriptomics and single‐cell RNA sequencing, this study identifies a novel subpopulation of SLPI⁺ AT2‐like cells at the invasive margin of lung adenocarcinoma (LUAD). These cells, through stromal crosstalk and Wnt pathway activation, promote tumor stemness and invasion.
Zhoufeng Wang, Guonian Zhu, Pan Tang, Yan Wang, Wenxin Luo, Wenpeng Song, Zhikang Pan, Bingjie Zheng, YongChao Jiang, Defu Xiao, Xin Jin, Yong Bai, Guowei Che, Weimin Li   +13 more
wiley   +1 more source