Results 261 to 270 of about 93,850 (311)

Immunometabolic Rewiring of Dendritic Cells to Overcome Glutamine‐Driven Immune Suppression in Colorectal Cancer

Advanced Science, EarlyView.
T26 is an immunometabolic prodrug that modulates colorectal cancer cells. It blocks glutamine metabolism and enhances STING signaling, which promotes the release of reprogrammed extracellular vesicles. These vesicles drive dendritic cell maturation and CD8⁺ T cell activation, thereby strengthening antitumor immunity and improving the effectiveness of ...
Bingjie Zhang, Renming Fan, Yongrui Hai, Ye Chen, Xintong Lu, Wenhui Wang, Jiarui Dou, Jiaxin Yan, Chang Su, Yue Chen, Le Yang, Minggao Zhao, Lei Liang, Gaofei Wei   +13 more
wiley   +1 more source

The Ethics of Tax Evasion: A Survey of Accounting, Business and Economics Students in Hong Kong

, 2006
Robert W. McGee, Simon S. M. Ho
openalex   +1 more source

Proteomic and Functional Analysis Reveals Temperature-Driven Immune Evasion Strategies of <i>Streptococcus iniae</i> in Yellowfin Seabream (<i>Acanthopagrus latus</i>). [PDF]

Biology (Basel)
Yang Y, Zhang G, Xu R, Deng Y, Mo Z, Li Y, Dan X.   +6 more
europepmc   +1 more source

ZDHHC2‐Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation

Advanced Science, EarlyView.
Our study reveals a novel mechanism by which palmitoylation regulates ferroptosis and enzalutamide resistance in prostate cancer. Under enzalutamide resistance, the FOXA1/CXXC5/TET2 complex induces aberrant upregulation of ZDHHC2, which subsequently suppresses ferroptosis by mediating S‐palmitoylation of USP19 and degradation of ACSL4 protein in CRPC ...
Shuai Shao, Wei Li, Yulong Hong, Ruijiang Zeng, Liang Zhu, Lu Yi, Yuan Li, Yinhuai Wang, Haojie Huang, Xuewen Jiang, Xin Jin   +10 more
wiley   +1 more source

Podocalyxin protects high grade serous ovarian cancer spheroids from NK cell infiltration and spheroid destruction. [PDF]

BMC Cancer
Tran NL, Wang Y, Quinn KM, Bilandzic M, Stephens A, Nie G.   +5 more
europepmc   +1 more source

Emerging Nanozyme Strategies for Precision Breast Cancer Treatment

Advanced Science, EarlyView.
Different types of nanozymes‐mediated chemotherapy, photothermal therapy, immunotherapy, and multiple combined therapies for the effective treatment of breast cancer. Abstract Breast cancer, the most common malignant tumor among women worldwide, poses a significant challenge to public health due to its high incidence and mortality rates.
Jian Zang, Zhaozhou Ren, Haibo Wang, Xing Yang, Yang Song, Jun Liao, Xiaoying Li   +6 more
wiley   +1 more source

Impaired and restored CD8⁺ T cell responses to a sequentially mutated spike epitope in Omicron variants. [PDF]

Front Immunol
Chung EJ, Park S, Kim SH, Choi JY, Jeong HS, Ko JH, Song JY, Lee YJ.   +7 more
europepmc   +1 more source

Pre‐Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS‐CoV‐2 Inactivated Vaccines

Advanced Science, EarlyView.
Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye, Xiaoli Zhang, Lingfeng Qiu, Jia Ji, Jueqing Gu, Hongyu Jia, Yingfeng Lu, Jiyang Chen, Zelu Meng, Jiangshan Lian, Hangping Yao, Xun Zeng, Yida Yang   +12 more
wiley   +1 more source

Target - The Elderly: A Nondiscrimination Perspective on Daniel Callahan\u27s Setting Limits [PDF]

, 1992
Destro, Robert A.
core   +1 more source

Separate Kingdoms, Same Conspiracies: Conserved Viral Strategies for Immune Evasion in Animal and Bacterial Hosts. [PDF]

MedComm (2020)
Wang J, He X, Li G.
europepmc   +1 more source