MARCO+ TAMs dominate restrained cytotoxicity of CD8+ CTLs and ICB resistance in RCC. Mechanically, MARCO impairs MHC‐I‐mediated neoantigen cross‐presentation via the SOCS1‐JAK1‐STAT1‐NLRC5 signaling cascade in TAMs. Targeted MARCO treatment boosts macrophage antigen cross‐presentation and empowers CD8+ T cells, thereby potentiating ICB efficacy ...
Jiayuan Chen +14 more
wiley +1 more source
Aquaglyceroporin-7 ameliorates sorafenib resistance and immune evasion in hepatocellular carcinoma through inhibition of lipid accumulation. [PDF]
He G +5 more
europepmc +1 more source
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang +17 more
wiley +1 more source
Coordinating oncogenesis and immune evasion: KPNA2, GOLM1, and TK1 as novel CAR T-cell targets in lung adenocarcinoma. [PDF]
Liu W +10 more
europepmc +1 more source
The Role of UFMylation in the Development and Progression of Gastric Cancer. [PDF]
Fang Y, Wu A, Cong YS, Li G.
europepmc +1 more source
CLEC3A Promotes Immune Evasion and Tumor Progression by Enhancing PD-L1 Stability to Weaken T Cell Cytotoxicity in Luminal Breast Cancer. [PDF]
Chen C +5 more
europepmc +1 more source
CAF-macrophage crosstalk fuels immunotherapy resistance. [PDF]
Liu Y, Wang L.
europepmc +1 more source
Spatially resolved endothelial signaling via nampt-itga5 drives immune evasion in stem-like gastric cancer. [PDF]
Sung JY, Cheong JH, Kim ET.
europepmc +1 more source
Multicenter validation of CEACAM6 and FOXP3 as robust prognostic biomarkers in colon cancer: Combined immunohistochemical and transcriptomic analysis. [PDF]
Liu Y, Ye J, Ma J, Pan X.
europepmc +1 more source

