Results 61 to 70 of about 1,505,743 (327)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Bio-mimetic high-speed target localization with fused frame and event vision for edge application

Frontiers in Neuroscience, 2022
Evolution has honed predatory skills in the natural world where localizing and intercepting fast-moving prey is required. The current generation of robotic systems mimics these biological systems using deep learning.
Ashwin Sanjay Lele, Yan Fang, Aqeel Anwar, Arijit Raychowdhury   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Instant Slow-Motion Visualization of High-Speed Phenomena Based on Event Camera

IEEE Access
High-speed phenomena are difficult to perceive due to human vision limitations, yet their immediate understanding is crucial in fields like sports refereeing and neurosciences.
Kotoka Matsunaga, Katsutoshi Masai, Hideo Saito   +2 more
doaj   +1 more source

Event-Based Stereo Depth Estimation Using Belief Propagation

Frontiers in Neuroscience, 2017
Compared to standard frame-based cameras, biologically-inspired event-based sensors capture visual information with low latency and minimal redundancy. These event-based sensors are also far less prone to motion blur than traditional cameras, and still ...
Zhen Xie, Zhen Xie, Shengyong Chen, Garrick Orchard, Garrick Orchard   +4 more
doaj   +1 more source

Efficient Camera-Based Pose Estimation for Real-Time Applications

, 2009
Accurate online localization is crucial for mobile robotics. In this paper, we describe a real-time image-based localization technique, which is based on a single calibrated camera.
Elmar Mair, Klaus H. Strobl, Michael Suppa, Mair, Elmar, Darius Burschka, Strobl, Klaus, Suppa, Michael, Burschka, Darius   +7 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Stereo Event-Based Visual–Inertial Odometry

Sensors
Event-based cameras are a new type of vision sensor in which pixels operate independently and respond asynchronously to changes in brightness with microsecond resolution, instead of providing standard intensity frames.
Kunfeng Wang, Kaichun Zhao, Wenshuai Lu, Zheng You   +3 more
doaj   +1 more source

More Accurate Pinhole Camera Calibration with Imperfect Planar Target

, 2011
This paper presents a novel approach to camera calibration that improves final accuracy with respect to standard methods using precision planar targets, even if now inaccurate, unmeasured, roughly planar targets can be used.
Hirzinger, Gerd, Klaus H. Strobl, Gerd Hirzinger, Strobl, Klaus H.   +3 more
core   +1 more source

Toward Hardware Spiking Neural Networks with Mixed-Signal Event-Based Learning Rules

, 2020
International audienceHardware spiking neural networks that co-integrate analog silicon neurons with memristive synaptic crossbar arrays are promising candidates to achieve low-power processing of event-based data.
Jean Tomas, Sylvain Sighi, Meyer, Charly, Adrien F. Vincent, Lewden, Pierre, Saïghi, Sylvain, Pierre Lewden, Charly Meyer, Vincent, Adrien, Tomas, Jean   +9 more
core   +1 more source