Results 141 to 150 of about 27,084,584 (305)

Event-Based Control and Estimation of Server Systems [Elektronisk resurs]

open access: yes, 2018
Feedback control is increasingly being applied in server systems to make them more robust and efficient. This includes managing quality of service, minimizing power consumption, and adapting to varying workloads. Successful adaptation and control in turn
Cervin, Anton,, Lund University.
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Based event model application research on configurable integrated platform

open access: yes, 2011
In the manufacturing execution system (Manufacture Execute System, MES), configurability, reconfiguration, expansibility has always been one of the difficulties to be solved.
Shi HB(史海波)   +5 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Event Processing in Web Service Runtime Environments

open access: yes, 2010
Service-oriented Architectures (SOA) and Web services have received a lot of attention from both industry and academia. Services as the core entities of every SOA are changing regularly based on various reasons.
Rosenberg, Florian   +3 more
core   +1 more source

A Scalable, Ultra-Low-Latency FPGA Accelerator for Neuromorphic Feature Extraction

open access: yesIEEE Access
Neuromorphic algorithms can extract features directly from an asynchronous event-based stream by exploiting complex spatio-temporal relationships without frame-reconstruction overhead.
Luke Kljucaric   +2 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Optimizing Database Performance in Complex Event Processing through Indexing Strategies

open access: yesData
Complex event processing (CEP) systems have gained significant importance in various domains, such as finance, logistics, and security, where the real-time analysis of event streams is crucial. However, as the volume and complexity of event data continue
Maryam Abbasi   +4 more
doaj   +1 more source

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