Results 151 to 160 of about 1,107,019 (309)

Internal Server State Estimation Using Event-based Particle Filtering [Elektronisk resurs]

open access: yes, 2018
Closed-loop control of cloud resources requires there to be measurements readily available from the process in order to use the feedback mechanism to form a control law. If utilizing state-feedback control, sought states might be unfeasible or impossible
Cervin, Anton,   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Optimizing Database Performance in Complex Event Processing through Indexing Strategies

open access: yesData
Complex event processing (CEP) systems have gained significant importance in various domains, such as finance, logistics, and security, where the real-time analysis of event streams is crucial. However, as the volume and complexity of event data continue
Maryam Abbasi   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Parallel discrete event simulation on the SpiNNaker engine

open access: yes, 2013
The SpiNNaker engine is a multiprocessor system, designed with a scalable interconnection system to perform real-time neural network simulation. The scalable property of the SpiNNaker system has the potential of providing high computation power making it
Chuan Bai, Bai, Chuan
core  

Content-based effective event matching algorithm

open access: yesTongxin xuebao, 2011
Based on the study of characteristics of the distributed virtual environment and current event matching algo-rithms,a content-based effective event matching(CEEM) algorithm was proposed.By considering the efficiency of both subscription processing and ...
CHEN Ji-ming1   +4 more
doaj   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

A novel pattern for complex event processing in RFID applications

open access: yes, 2008
This study investigates Complex Event Processing (CEP) Pattern on Radio-Frequency Identification (RFID) applications. RFID technolgy has brought tremendous benefits for the business by incorporating RFID data into supply chain planning and business ...
Zhu YL(朱云龙)   +3 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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