Results 51 to 60 of about 10,705,458 (263)

Topographic Mapping of P300 and Frontal Cognitive Function in Parkinson’s Disease

Behavioural Neurology, 2000
The purpose of this study was to evaluate the relationship between P300 that is one of the event-related potentials and frontal cognitive functions in Parkinson’s disease (PD) without clinically apparent dementia.
Mutsumi Iijima, Mikio Osawa, Makoto Iwata, Akiko Miyazaki, Hideaki Tei   +4 more
doaj   +1 more source

Event‐Related Oscillations Versus Event‐Related Potentials in a P300 Task as Biomarkers for Alcoholism [PDF]

Alcoholism: Clinical and Experimental Research, 2010
Objective:  It has been proposed that event‐related oscillation (ERO) measures of EEG activity recorded in P300 tasks provide more powerful biomarkers of alcoholism than event‐related potential (ERP) measures. This study examines this question in a group of long‐term abstinent alcoholics (LTAAs).Methods:  EEGs were recorded on 48 LTAAs and 48 age and ...
Colin, Andrew, George, Fein
openaire   +2 more sources

Glucose and Glutamine Deprivation Promotes Breast Cancer Lung Metastasis via BRD4‐Dependent Enhancer Activation

Advanced Science, EarlyView.
To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai, Arathy Vasukutty, Yujin Na, Sung‐Chul Lim, Hong Seok Choi   +4 more
wiley   +1 more source

P300 Modulation via Transcranial Alternating Current Stimulation in Adult Attention-Deficit/Hyperactivity Disorder: A Crossover Study

Frontiers in Psychiatry, 2022
ObjectiveA repeated finding regarding event-related potentials (ERPs) is that patients with ADHD show a reduced P300 amplitude. This raises the question of whether the attention of ADHD patients can be increased by stabilizing the P300. Assuming that the
Kyra Kannen, Behrem Aslan, Cindy Boetzel, Christoph S. Herrmann, Silke Lux, Helena Rosen, Benjamin Selaskowski, Annika Wiebe, Alexandra Philipsen, Niclas Braun   +9 more
doaj   +1 more source

Characterization of N200 and P300: Selected Studies of the Event-Related Potential [PDF]

International Journal of Medical Sciences, 2005
The Event-Related Potential (ERP) is a time-locked measure of electrical activity of the cerebral surface representing a distinct phase of cortical processing. Two components of the ERP which bear special importance to stimulus evaluation, selective attention, and conscious discrimination in humans are the P300 positivity and N200 negativity, appearing
Salil H, Patel, Pierre N, Azzam
openaire   +2 more sources

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

When "It" becomes "Mine": attentional biases triggered by object ownership. [PDF]

, 2011
Previous research has demonstrated that higher-order cog- nitive processes associated with the allocation of selective atten- tion are engaged when highly familiar self-relevant items are encountered, such as oneðs name, face, personal possessions and ...
Brebner, Joanne, Kim van Bussel, Toma, Andreea, Olav Krigolson, van Bussel, Kim, Joanne L. Brebner, David J. Turk, Krigolson, Olave, Andreea S. Toma, Handy, Todd, Turk, David J, Todd C. Handy   +11 more
core   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

Advanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian, Shuoyao Ma, Bo Yang, Fei Gao, Hao Guo, Haixiao Liu, Xun Wu, Wenxing Cui, Jingyu Dong, Qian Lin, Yufeng Ge, Jin Ma, Jiazhen Zhao, Yongzhi Zhang, Dongzhi Xue, Jiaxin Tian, Ziwen Zhang, Kai Wang, Meng Xu, Dayun Feng, Jinpeng Zhou, Yan Qu   +21 more
wiley   +1 more source

Art expertise modulates the emotional response to modern art, especially abstract: An ERP investigation [PDF]

, 2015
Art is one of life’s great joys, whether it is beautiful, ugly, sublime or shocking. Aesthetic responses to visual art involve sensory, cognitive and visceral processes.
Elizabeth Orme, Ellis, Jason, Orme, Elizabeth, Jane E. Else, Else, Jane, Jason Ellis   +5 more
core   +1 more source