Results 121 to 130 of about 396,275 (278)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Transfer of artificial syntax functions among equivalence - related stimuli: An event - related brain potentials study [PDF]

, 2015
La formación de clases de equivalencia entre estímulos ha sido propuesta en el campo del Análisis Experimental del Comportamiento como un prerrequisito conductual para el lenguaje. Adicionalmente, existe evidencia de que la transferencia de función entre
Tabullo, Angel Javier, Wainselboim, Alejandro Javier, Yorio, Alberto, Zanutto, Silvano   +3 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Age-related differences on event-related potentials and brain rhythm oscillations during working memory activation [PDF]

, 2018
Previous functional imaging studies have pointed to the compensatory recruitment of cortical circuits in old age in order to counterbalance the loss of neural efficiency and preserve cognitive performance.
Deiber, Marie-Pierre, Fazio-costa, Lara, Giannakopoulos, Panteleimon, Gold, Gabriel, Herrmann, François, Millet, Phiippe, Missonnier, Pascal, Rodriguez, Christelle   +7 more
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Event-related potentials to overlapping shapes: Effects of saliency and interference [PDF]

, 2010
A. Delorme, A. J. Bell, A. J. Pegna, American Electrophysiological Society, B. A. Eriksen, B. Kopp, Benoit A. Bacon, D. Navon, Franco Lepore, G. M. Doniger, G. Volberg, J. Bruno Debruille, J. Bullier, J. M. Brown, J. Onton, J. R. Stroop, J. Wagemans, K. R. Gegenfurtner, L. C. Boer, L. M. Ward, L. Paquet, Louis Renoult, M. Brodeur, M. Brodeur, M. Brodeur, M. Liotti, M. M. Murray, Mathieu B. Brodeur, P. J. Kellman, R. West, S. Han, S. Han, S. Han, S. Han, S. Makeig, S. W. Greenhouse, V. Veen Van, W. J. Gehring   +37 more
core   +1 more source

Mental workload measurement: Event-related potentials and ratings of workload and fatigue [PDF]

Event-related potentials were elicited when a digitized word representing a pilot's call-sign was presented. This auditory probe was presented during 27 workload conditions in a 3x3x3 design where the following variables were manipulated: short-term load,
Biferno, M. A.
core   +1 more source