Results 1 to 10 of about 56,624 (164)

p300/CBP and cancer [PDF]

open access: yesOncogene, 2004
p300 and cyclic AMP response element-binding protein (CBP) are adenoviral E1A-binding proteins involved in multiple cellular processes, and function as transcriptional co-factors and histone acetyltransferases. Germline mutation of CBP results in Rubinstein-Taybi syndrome, which is characterized by an increased predisposition to childhood malignancies.
N Gopalakrishna Iyer   +2 more
exaly   +3 more sources

TRIM25 targets p300 for degradation

open access: yesLife Science Alliance, 2023
Here, it is shown that the E3 protein TRIM25 targets the transcriptional co-activator p300 in an ubiquitin-independent manner for proteasomal degradation involving the motor protein dynein. p300 is an important transcriptional co-factor.
Seham Elabd   +6 more
doaj   +1 more source

Advances in P300 brain–computer interface spellers: toward paradigm design and performance evaluation

open access: yesFrontiers in Human Neuroscience, 2022
A brain-computer interface (BCI) is a non-muscular communication technology that provides an information exchange channel for our brains and external devices. During the decades, BCI has made noticeable progress and has been applied in many fields.
Jiahui Pan   +5 more
doaj   +1 more source

Correlation of Auditory Event Related Potential (P300) and Mini Mental State Examination to Measure Cognitive Function in Healthy Young Adults: A Pilot Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Cognition is composed of intellectual function, memory, speech and language, complex perception, orientation, attention, judgment, planning and decision-making. Behaviour is the exhibition of these cognitive functions.
Jitender Sorout   +3 more
doaj   +1 more source

MicroRNA-20a constrains p300-driven myocardial angiogenic transcription by direct targeting of p300. [PDF]

open access: yesPLoS ONE, 2013
To characterize downstream effectors of p300 acetyltransferase in the myocardium.Acetyltransferase p300 is a central driver of the hypertrophic response to increased workload, but its biological targets and downstream effectors are incompletely known ...
Lina A Shehadeh   +9 more
doaj   +1 more source

P300 cognitive assessment in patients with first-episode psychosis: a prospective case-control study

open access: yesMiddle East Current Psychiatry, 2020
Background Several studies using event-related potential (ERP) methods have reported a relationship between the cognitive dysfunction of patients with psychosis and P300 latency and amplitude.
Wageeh A. Hassan   +6 more
doaj   +1 more source

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels

open access: yesScientific Reports, 2023
The activation of stress response pathways in synovial fibroblasts (SF) is a hallmark of rheumatoid arthritis (RA). CBP and p300 are two highly homologous histone acetyl transferases and writers of activating histone 3 lysine 27 acetylation (H3K27ac ...
Monika Krošel   +9 more
doaj   +1 more source

A New Paradigm for Region-Based P300 Speller in Brain Computer Interface

open access: yesIEEE Access, 2019
Electroencephalography-based brain computer interface systems could provide alternative communication methods for severely disabled people who cannot use their neuromuscular systems.
Zeki Oralhan
doaj   +1 more source

Habituation and Dishabituation of P300

open access: yesCognitive and Behavioral Neurology, 2006
We aimed to see the consequences of habituation and posthabituation by means of repeatedly measuring the effects over a longer period.The study was performed on 27 healthy volunteers. The event-related potentials were recorded from the Fz, the Cz, and the Pz electrode sites. The rare tone-frequent tone probability ratio was 20%. All subjects were asked
Keçeci, Hulusi   +2 more
openaire   +3 more sources

Brain Painting: first evaluation of a new brain-computer interface application with ALS patients and healthy volunteers.

open access: yesFrontiers in Neuroscience, 2010
Brain-computer interfaces (BCI) enable paralyzed patients to communicate; however, up to date, no creative expression was possible. The current study investigated the accuracy and user friendliness of P300-Brain Painting, a new BCI-application developed ...
Jana I. Muenssinger   +9 more
doaj   +1 more source

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