P300 enhances glycolysis and dox resistance in DLBCL by upregulating HK2 expression through histone lactylation [PDF]
BMC CancerBackground Diffuse large B-cell lymphoma (DLBCL), the most common lymphocytic malignancy, faces treatment challenges due to drug resistance. Glycolysis has been implicated in tumor resistance, whereas P300, an epigenetic regulator, is known to facilitate
Xiangxiang Song +4 more
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TRIM25 targets p300 for degradation
Life Science Alliance, 2023 Here, it is shown that the E3 protein TRIM25 targets the transcriptional co-activator p300 in an ubiquitin-independent manner for proteasomal degradation involving the motor protein dynein. p300 is an important transcriptional co-factor.
Seham Elabd +6 more
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Frontiers in Human Neuroscience, 2022 A brain-computer interface (BCI) is a non-muscular communication technology that provides an information exchange channel for our brains and external devices. During the decades, BCI has made noticeable progress and has been applied in many fields.
Jiahui Pan +5 more
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Correlation of Auditory Event Related Potential (P300) and Mini Mental State Examination to Measure Cognitive Function in Healthy Young Adults: A Pilot Study [PDF]
Journal of Clinical and Diagnostic Research, 2020 Introduction: Cognition is composed of intellectual function, memory, speech and language, complex perception, orientation, attention, judgment, planning and decision-making. Behaviour is the exhibition of these cognitive functions.
Jitender Sorout +3 more
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P300 cognitive assessment in patients with first-episode psychosis: a prospective case-control study
Middle East Current Psychiatry, 2020 Background Several studies using event-related potential (ERP) methods have reported a relationship between the cognitive dysfunction of patients with psychosis and P300 latency and amplitude.
Wageeh A. Hassan +6 more
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MicroRNA-20a constrains p300-driven myocardial angiogenic transcription by direct targeting of p300. [PDF]
PLoS ONE, 2013 To characterize downstream effectors of p300 acetyltransferase in the myocardium.Acetyltransferase p300 is a central driver of the hypertrophic response to increased workload, but its biological targets and downstream effectors are incompletely known ...
Lina A Shehadeh +9 more
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Scientific Reports, 2023 The activation of stress response pathways in synovial fibroblasts (SF) is a hallmark of rheumatoid arthritis (RA). CBP and p300 are two highly homologous histone acetyl transferases and writers of activating histone 3 lysine 27 acetylation (H3K27ac ...
Monika Krošel +9 more
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Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase [PDF]
, 2017 Human p300 is a polyhedric transcriptional coactivator, playing a crucial role by acetylating histones on specific lysine residues. A great deal of evidences shows that p300 is involved in several diseases as leukemia, tumors and viral infection.
Alberter +49 more
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A New Paradigm for Region-Based P300 Speller in Brain Computer Interface
IEEE Access, 2019 Electroencephalography-based brain computer interface systems could provide alternative communication methods for severely disabled people who cannot use their neuromuscular systems.
Zeki Oralhan
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Effect of inhibition indexed by auditory P300 on transmission of visual sensory information.
PLoS ONE, 2021 Early electroencephalographic studies that focused on finding brain correlates of psychic events led to the discovery of the P300. Since then, the P300 has become the focus of many basic and clinical neuroscience studies.
Amirmahmoud Houshmand Chatroudi +3 more
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