Results 121 to 130 of about 3,028,845 (288)
Demographics and consumer behaviour of visitors to the Wegry/Drive Out Bull Run motorsport event [PDF]
African Journal of Hospitality, Tourism and Leisure, 2019 It is generally accepted that the event tourism industry has a positive economic impact on countries and local communities alike, especially in developing countries such as South Africa, where events and event tourism are essential drivers for economic ...
Mavis Chamboko Mpotaringa +1 more
doaj
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The composition of Event-B models [PDF]
The transition from classical B [2] to the Event-B language and method [3] has seen the removal of some forms of model structuring and composition, with the intention of reinventing them in future. This work contributes to thatreinvention.
Michael Poppleton, Poppleton, Michael
core +1 more source
Frontiers in NeuroinformaticsIntroductionAutomated seizure detection promises to aid in the prevention of SUDEP and improve the quality of care by assisting in epilepsy diagnosis and treatment adjustment.MethodsIn this phase 2 exploratory study, the performance of a contactless ...
Pragya Rai +13 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Feature composition - towards product lines of event-B models [PDF]
, 2009 Event-B is a formal language for modelling reactive systems, based on set theory and first-order logic. The RODIN toolkit provides comprehensive tool support for modelling and refinement in Event-B, analysis and verification using animator/model-checkers
Snook, Colin +2 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source