Results 131 to 140 of about 3,028,845 (288)

Historia cultural estadounidense desde el factor religioso: fallos de americaness y sus velos / American Cultural History under the religious factor: Americaness crack & veils

open access: yesCauriensia, 2017
ResumenEste estudio evalúa la idiosincrasia estadounidense, revisándose la evolución de su visión y misión propias (sus características ideas y creencias, ritos y símbolos, relaciones Iglesia-Estado, despertares sociales y revitalizaciones elitistas, etc.
Antonio Sánchez-Bayón   +2 more
doaj   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Event experiences: design, management and impact [PDF]

open access: yes
The papers submitted for this PhD by publication represent research centered on event experiences and their design, management and impact. They are the result of research projects that have produced seven published peer-reviewed papers and one book.
Berridge, Graham
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Perceived Authenticity and Tourist Behavior Toward Local Restaurants: An Empirical Study in Thailand

open access: yesTourism and Hospitality
Tourist behavior is evolving rapidly, and local restaurants must develop strategies to capture the attention of these changing tourists. This study, conducted in Thailand, investigates the relationships between perceived authenticity, consumer self ...
Sukanya Wareebor   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tasking Event-B: An Extension to Event-B for Generating Concurrent Code [PDF]

open access: yes
The Event-B method is a formal approach for modelling systems in safety-, and business-critical, domains. Initially, system specification takes place at a high level of abstraction; detail is added in refinement steps as the development proceeds toward ...
Edmunds, Andrew, Butler, Michael
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Event Structure [PDF]

open access: yes
This study establishes a relation between the semantics of the subject and the direct object-NP and aspect. The notion of event is central. Events have a beginning and an end.
Voorst, Jan van.
core  

Supporting reuse mechanisms for developments in event-b: composition [PDF]

open access: yes, 2009
The development of specifications often is a combination of smaller sub-components. Focusing on reuse, an interesting perspective is to formally define the combination of sub-components through refinement steps, reusing their properties and generating ...
Silva, Renato, Butler, Michael
core  

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