Results 61 to 70 of about 28,127 (288)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Autobiasing Event Cameras

This paper presents an autonomous method to address challenges arising from severe lighting conditions in machine vision applications that use event cameras. To manage these conditions, the research explores the built in potential of these cameras to adjust pixel functionality, named bias settings.
Mehdi Sefidgar Dilmaghani, Waseem Shariff, Cian Ryan, Joseph Lemley, Peter Corcoran 0001   +4 more
openaire   +2 more sources

Simultaneous Mosaicing and Tracking with an Event Camera [PDF]

Proceedings of the British Machine Vision Conference 2014, 2014
An event camera is a silicon retina which outputs not a sequence of video frames like a standard camera, but a stream of asynchronous spikes, each with pixel location, sign and precise timing, indicating when individual pixels record a threshold log intensity change.
Hanme Kim, Ankur Handa, Ryad Benosman, Sio-Hoi Ieng, Andrew J. Davison   +4 more
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Denoising Method Based on Salient Region Recognition for the Spatiotemporal Event Stream

Sensors, 2023
Event cameras are the emerging bio-mimetic sensors with microsecond-level responsiveness in recent years, also known as dynamic vision sensors. Due to the inherent sensitivity of event camera hardware to light sources and interference from various ...
Sichao Tang, Hengyi Lv, Yuchen Zhao, Yang Feng, Hailong Liu, Guoling Bi   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Motion-aware Event Suppression for Event Cameras

CoRR
In this work, we introduce the first framework for Motion-aware Event Suppression, which learns to filter events triggered by IMOs and ego-motion in real time. Our model jointly segments IMOs in the current event stream while predicting their future motion, enabling anticipatory suppression of dynamic events before they occur.
Roberto Pellerito, Nico Messikommer, Giovanni Cioffi, Marco Cannici, Davide Scaramuzza 0001   +4 more
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Hough Transform Implementation For Event-Based Systems: Concepts and Challenges

Frontiers in Computational Neuroscience, 2018
Hough transform (HT) is one of the most well-known techniques in computer vision that has been the basis of many practical image processing algorithms. HT however is designed to work for frame-based systems such as conventional digital cameras. Recently,
Sajjad Seifozzakerini, Sajjad Seifozzakerini, Wei-Yun Yau, Kezhi Mao, Hossein Nejati   +4 more
doaj   +1 more source