Results 121 to 130 of about 396,760 (264)

Structural and functional hepatic factors as prognostic indicators in children with Langerhans cell histiocytosis. [PDF]

Front Oncol
Hassan S, Sedky MSM, Salama A, Zaky I, Girguis H, Abd ELKarim S, ELHaddad A.   +6 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Clarifying the Scope of Native EHRA Type 2 Valvular Disease and Event Reporting in Anticoagulated Patients With Atrial Fibrillation. [PDF]

Clin Cardiol
Chen J, Xu M.
europepmc   +1 more source

Probability of events involving logical aspects

, 2018
In this article, we study the Probability's knowledge of prospective primary school teachers, when there are logical aspects involved in the formulation of events. Forty-six students participated in the study, from a University in Northern Portugal, who had to resolve a three-item task in the context of a formal evaluation: the first one, on the union ...
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Liver involvement in pediatric acute leukemia: subtype differences and complex hepatic injury as a novel marker for AML risk stratification. [PDF]

Front Oncol
Xue YJ, Wang Y, Lu AD, Jia YP, Zhang ZX, Zhang L, Cao X, Zhang LP, Zeng HM.   +8 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Relapse risk of lupus-related serositis according to immunosuppressive therapy: a national real-world study. [PDF]

RMD Open
Fels E, Goncalves C, Jousse-Joulin S, Chiche L, Korganow AS, Martin T, Arnaud L, Ottaviani S, Lazaro E, Sibilia J, Trefond L, Scherlinger M.   +11 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Uncovering unmet needs in healthcare teams: a cross-sectional study on the second victim phenomenon. [PDF]

Isr J Health Policy Res
Fisher S, Djerassi R, Gendler Y, Pirogovsky A, Dreiher J.   +4 more
europepmc   +1 more source