Results 71 to 80 of about 210,628 (307)

Scintillation in Low-Temperature Particle Detectors

Physics, 2021
Inorganic crystal scintillators play a crucial role in particle detection for various applications in fundamental physics and applied science. The use of such materials as scintillating bolometers, which operate at temperatures as low as 10 mK and detect
Denys Poda
doaj   +1 more source

The Heavy Photon Search (HPS) Software Environment [PDF]

EPJ Web of Conferences, 2020
The Heavy Photon Search (HPS) is an experiment at the Thomas Jefferson National Accelerator Facility (JLab) designed to search for a hidden sector photon (A’) in fixed-target electro-production.
Graf Norman
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Machine Learning Approach for Event Position Reconstruction in the DEAP-3600 Dark Matter Search Experiment

Physics, 2023
In addition to classical analytical data processing methods, machine learning methods are widely used for data analysis in elementary particle physics.
DEAP Collaboration
doaj   +1 more source

Sinking particle flux and physical-biological oceanographic dataset during ENSO event (1997-1999) in the South China Sea

, 2021
The file DS01_改 is a replacement of the previous file named DS01 in responses to the comments during the review ...
Li H., L., Wiesner M., G., Chen J., F.
openaire   +1 more source

Baryon production from cluster hadronisation

European Physical Journal C: Particles and Fields, 2018
We present an extension to the colour reconnection model in the Monte Carlo event generator Herwig to account for the production of baryons and compare it to a series of observables for soft physics.
Stefan Gieseke, Patrick Kirchgaeßer, Simon Plätzer   +2 more
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

XENONnT analysis: Signal reconstruction, calibration, and event selection [PDF]

Physical Review D
The XENONnT experiment, located at the INFN Laboratori Nazionali del Gran Sasso, Italy, features a 5.9 tonne liquid xenon time projection chamber surrounded by an instrumented neutron veto, all of which is housed within a muon veto water tank. Because of
E. Aprile, J. Aalbers, K. Abe, S. Ahmed Maouloud, L. Althueser, B. Andrieu, E. Angelino, J. Angevaare, D. Antón Martin, F. Arneodo, L. Baudis, M. Bazyk, L. Bellagamba, R. Biondi, A. Bismark, K. Boese, A. Brown, G. Bruno, R. Budnik, J. M. Cardoso, A. Cimental Chávez, A. Colijn, J. Conrad, J. Cuenca-García, V. D’Andrea, L. Daniel Garcia, M. Decowski, A. Deisting, C. Di Donato, P. Di Gangi, S. Diglio, K. Eitel, A. Elykov, A. Ferella, C. Ferrari, H. Fischer, T. Flehmke, M. Flierman, W. Fulgione, C. Fuselli, P. Gaemers, R. Gaior, M. Galloway, F. Gao, S. Ghosh, R. Giacomobono, R. Glade-Beucke, L. Grandi, J. Grigat, H. Guan, M. Guida, P. Gyorgy, R. Hammann, A. Higuera, C. Hils, L. Hoetzsch, N. Hood, M. Iacovacci, Y. Itow, J. Jakob, F. Joerg, Y. Kaminaga, M. Kara, P. Kavrigin, S. Kazama, M. Kobayashi, D. Koke, A. Kopec, F. Kuger, H. Landsman, R. Lang, L. Levinson, I. Li, S. Li, S. Liang, Y.-T. Lin, S. Lindemann, M. Lindner, K. Liu, J. Loizeau, F. Lombardi, J. Long, J. Lopes, T. Luce, Y. Ma, C. Macolino, J. Mahlstedt, A. Mancuso, L. Manenti, F. Marignetti, T. Marrodán Undagoitia, K. Martens, J. Masbou, E. Masson, S. Mastroianni, A. Melchiorre, J. Merz, M. Messina, A. Michael, K. Miuchi, A. Molinario, S. Moriyama, K. Morå, Y. Mosbacher, M. Murra, J. Müller, K. Ni, U. Oberlack, B. Paetsch, Y. Pan, Q. Pellegrini, R. Peres, C. Peters, J. Pienaar, M. Pierre, G. Plante, T. Pollmann, L. Principe, J. Qi, J. Qin, D. Ramírez García, M. Rajado, R. Singh, L. Sanchez, J. dos Santos, I. Sarnoff, G. Sartorelli, J. Schreiner, D. Schulte, P. Schulte, H. Schulze Eißing, M. Schumann, L. Scotto Lavina, M. Selvi, F. Semeria, P. Shagin, S. Shi, J. Shi, M. Silva, H. Simgen, A. Takeda, P. Tan, A. Terliuk, D. Thers, F. Toschi, G. Trinchero, C. Tunnell, F. Tönnies, K. Valerius, S. Vecchi, S. Vetter, F. Villazon Solar, G. Volta, C. Weinheimer, M. Weiss, D. Wenz, C. Wittweg, V. Wu, Y. Xing, D. Xu, Z. Xu, M. Yamashita, L. Yang, J. Ye, L. Yuan, G. Zavattini, M. Zhong   +166 more
semanticscholar   +1 more source