Results 121 to 130 of about 3,483,849 (299)

Chain event graphs : theory and application [PDF]

open access: yes
This thesis is concerned with the Graphical model known as the Chain Event Graph (CEG) [1][60][61], and develops the theory that appears in the currently published papers on this work.
Thwaites, Peter
core  

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

On the Event-based Attack-tolerant Control: A Polytopic Representation

open access: yes, 2019
peer reviewedIn the present contribution, we present a new event-based control representation. Based on the polytopic approach, more specifically the sector nonlinear transformation, an event-based attack-tolerant control, and scheduling co-design ...
VOOS, Holger   +3 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Long-term object tracking with a moving event camera

open access: yes, 2018
This paper presents a long-term object tracking algorithm for event cameras. A first of its kind for these revolutionary cameras, the tracking framework uses a discriminative representation for the object with online learning, and detects and re-tracks ...
Zhang, Shihao   +5 more
core  

A Comparison of Event Representations in DEFT [PDF]

open access: yesProceedings of the Fourth Workshop on Events, 2016
Ann Bies   +10 more
openaire   +2 more sources

Representation of Events and Rules in Gamification Systems

open access: yesProcedia Computer Science, 2018
Abstract The paper proposes a domain-agnostic description of user-generated events which conveys their key properties of relevance for gamification (i.a. context, actor, action, object, location and time) and a notation, based on this description, which allows to effectively specify gamification rules depending only on the content of the generated ...
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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