Results 101 to 110 of about 3,391,200 (289)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
High-Order Areas and Auditory Cortex Both Represent the High-Level Event Structure of Music. [PDF]
J Cogn Neurosci, 2022 Williams JA +6 more
europepmc +1 more source
Hadronic event structure, power corrections and the strong coupling at LEP
, 2002 Infrared and collinear events shapes are suited to directly probe properties of hard QCD. They are traditionally used to measure the strong coupling and to test the gauge structure of QCD. Perturbative predictions exist in several variations all of which
Wicke, D.
core +2 more sources
Representing Dependencies in Event Structures [PDF]
Logical Methods in Computer Science, 2019 Event structures where the causality may explicitly change during a computation have recently gained the stage. In this kind of event structures the changes in the set of the causes of an event are triggered by modifiers that may add or remove dependencies, thus making the happening of an event contextual.
openaire +5 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Decomposition Structures for Event-B [PDF]
, 2009 Event-B provides a flexible approach to modelling and refinement of systems. In this paper we outline two important ways in which Event-B refinement can be augmented with additional structuring to support further the management of complex refinements.
openaire +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
QCD--Instanton Induced Final States in Deep Inelastic Scattering [PDF]
, 1995 We report briefly on a broad and systematic study of possible manifestations of QCD-instantons at HERA. We concentrate on the high multiplicity final state structure, reminiscent of an isotropically decaying ``fireball''.
Gibbs, M., Ringwald, A., Schrempp, F.
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source