Results 121 to 130 of about 731,022 (305)

Chain event graphs : theory and application [PDF]

This thesis is concerned with the Graphical model known as the Chain Event Graph (CEG) [1][60][61], and develops the theory that appears in the currently published papers on this work.
Thwaites, Peter
core  

Transitivity and self-caused readings in Spanish deverbal nouns

Linguistica Brunensia, 2017
This paper examines the structural properties underlying the distribution and interpretation of two types of deverbal nouns in Spanish: miento nominals (e.g. hundimiento 'the sinking') and do/da nominals (e.g.
Natalia Jardón
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Evaluating the capacity of clinical pathways through discrete-event simulation. [PDF]

Organizing a medical facility efficiently is hard due to the numerous patient trajectories and their use of joint and scarce resources. Moreover, these trajectories tend to be complex and characterized by uncertain medical processes.
Cardoen, Brecht, Demeulemeester, Erik
core  

Implementation of supersymmetric processes in the HERWIG event generator

, 2002
We describe the implementation of supersymmetric processes in the HERWIG Monte Carlo event generator. We define relevant parameter and mixing conventions and list the hard scattering matrix elements.
Odagiri, K., Seymour, M.H., Moretti, S, Webber, B.R., Richardson, Peter, Odagiri, Kosuke, Seymour, Michael H., Odagiri, K, Moretti, Stefano, Moretti, S., Webber, Bryan R., Richardson, P., Webber, Bryan R, Seymour, Michael H   +13 more
core   +1 more source

Spatial structures in event-place formation

Journal of Architecture and Urbanism
Event-places occupy different physical layouts, but we lack a comprehensive understanding of their structures and arrangements. This study aims to uncover some of these patterns by examining various urban spaces recognized as event-places.
Manoochehr Moazzami, Faezeh Tafreshi
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Modular control-loop detection

, 2006
This paper presents an efficient algorithm to detect control-loops in large finite-state systems. The proposed algorithm exploits the modular structure present in many models of practical relevance, and often successfully avoids the explicit ...
Malik, Robi, Malik, Petra
core   +1 more source

Diffusion processes and event history analysis [PDF]

Several authors (e.g., Brüderl, Diekmann, Yamaguchi) derive hazard rate models of event history analysis from social diffusion processes. This paper also focuses on the integration of diffusion research and survival analysis.
Norman Braun, Henriette Engelhardt
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source