Results 101 to 110 of about 5,530,700 (284)

Decomposition Tool for Event-B

open access: yes
Two methods have been identified for Event-B model decomposition: shared variable and shared event. The purpose of this paper is to introduce the two approaches and the respective tool support in the Rodin platform. Besides alleviating the complexity for
Silva, Renato   +3 more
core   +1 more source

Modification of Jet Structure in High-Multiplicity pp Collisions due to Multiple-Parton Interactions and Observing a Multiplicity-Independent Characteristic Jet Size

open access: yesAdvances in High Energy Physics, 2019
We study the multiplicity dependence of jet structures in pp collisions using Monte Carlo event generators. We give predictions for multiplicity-differential jet structures and present evidence for a nontrivial jet shape dependence on charged hadron ...
Zoltán Varga   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

REFERENCES FOR CREATING A SCENARIO FOR MANAGEMENT OF EMERGENCY SITUATIONS [PDF]

open access: yesJournal of Defense Resources Management, 2019
Emergency situations are those events which, by their appearance and development, prevent the maintenance of a security environment conductively to daily activities and their removal is a complex process that involves the use of various quantitative ...
Andrei-Sergiu MAZURU, Dorel BADEA
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Archaeomagnetic evidence indicates post-Inka reheating of metallurgical kilns at Quillay (NW Argentina).

open access: yesPLoS ONE
This study presents an archaeomagnetic analysis of five metallurgical kilns from the settlement of Quillay (Catamarca, NW Argentina), attributed to the Inka period on the basis of radiocarbon dates and archaeological evidence. All five structures yielded
Judit Del Río   +7 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The effect of language structures in social event attribution among L2 English learner

open access: yesActa Psychologica
This article investigates whether English positive-negative alternating causal clauses and active-passive alternating syntactic structures make a difference in social event attribution of Chinese-L1 English-L2 learners.
Chengping Xu, Xiangru Meng
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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