Results 51 to 60 of about 6,645 (198)

Long‐term use of lokivetmab in dogs with atopic dermatitis

Veterinary Dermatology, Volume 35, Issue 6, Page 683-693, December 2024.
Background – Lokivetmab, a caninised monoclonal antibody against interleukin (IL)‐31, is an effective treatment for the pruritus associated with canine atopic dermatitis (cAD). Objectives – To investigate the efficacy and safety of lokivetmab during long‐term treatment defined as at least three consecutive lokivetmab injections in atopic dogs under ...
Bettina Kasper, Yury Zablotski, Ralf S. Mueller   +2 more
wiley   +1 more source

Eventos adversos em pacientes cirúrgicos: Revisão integrativa

Research, Society and Development, 2021
Objetivo: analisar as evidências científicas acerca dos eventos adversos ocorridos em pacientes cirúrgicos. Método: revisão integrativa de literatura, com coleta de dados de setembro a outubro de 2020, em três bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Medical Literature Analysis and Retrieval System Online ...
Andressa dos Santos, Natielen Pierobon, Fernanda Aparecida Zarichen, Gabriela Luísa Wibbelt, Ana Paula Moro Bertoni, Camila do Carmo Mota, Luzia Souza Evangelista Pulcini, Silvelly Peres Teixeira, Bruna Eloise Lenhani, Larissa Marcondes, Josemar Batista   +10 more
openaire   +2 more sources

Applying the Estimand Framework to Non‐Inferiority Trials

Pharmaceutical Statistics, Volume 23, Issue 6, Page 1156-1165, November/December 2024.
ABSTRACT Most published applications of the estimand framework have focused on superiority trials. However, non‐inferiority trials present specific challenges compared to superiority trials. The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use notes in their addendum on estimands and sensitivity ...
Helle Lynggaard, Oliver N. Keene, Tobias Mütze, Sunita Rehal   +3 more
wiley   +1 more source

Carfilzomib‐Induced Thrombotic Microangiopathy—Two Case Reports

Cancer Reports, Volume 7, Issue 10, October 2024.
ABSTRACTBackgroundThrombotic microangiopathy (TMA) is a pathological syndrome characterized by a combination of three key features: microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and organ damage, primarily affecting the kidneys. There are several drugs known to have a definite or probable causal association with TMA, and carfilzomib, a ...
Irene Attucci, Sofia Pilerci, Maria Messeri, Ludovica Pengue, Giulia Tomasino, Leonardo Caroti, Alessandro M. Vannucchi, Elisabetta Antonioli   +7 more
wiley   +1 more source

A placebo‐controlled, double‐blind study evaluating the effect of orally administered polyunsaturated fatty acids on the oclacitinib dose for atopic dogs

Veterinary Dermatology, Volume 35, Issue 4, Page 408-417, August 2024.
Background – Supplementation of polyunsaturated fatty acids (PUFA) enables dose reduction of prednisolone and ciclosporin in canine atopic dermatitis (cAD). Objective – To determine if oral administration of PUFA can reduce the dose of oclacitinib for cAD. Conclusion – Oral supplementation of PUFA allowed dose reduction of oclacitinib and improved pVAS,
Laura Schäfer, Nina Thom
wiley   +1 more source

Rastreadores para a busca ativa de eventos adversos a medicamentos em recém-nascidos

Cadernos de Saúde Pública, 2018
O objetivo foi verificar a aplicação e o desempenho dos rastreadores para a busca ativa de eventos adversos a medicamentos em recém-nascidos hospitalizados. Trata-se de um estudo de coorte prospectivo.
Sandra de Carvalho Fabretti, Sandra Cristina Brassica, Marco Antonio Cianciarullo, Nicolina Silvana Romano-Lieber   +3 more
doaj   +1 more source

Eventos adversos pós-vacinais e resposta social [PDF]

História, Ciências, Saúde-Manguinhos, 2003
A grande maioria das polêmicas públicas relativas a hipotéticos malefícios provocados pelas vacinas é extensão de controvérsias e discussões que surgem no próprio meio médico. Exemplos são os malefícios do mercúrio contido em várias vacinas, como a tríplice viral (MMR), provocando doença inflamatória intestinal e autismo; a vacina contra hepatite B e ...
Martins, Reinaldo Menezes, Maia, Maria de Lourdes de Souza   +1 more
openaire   +3 more sources

Relationship between two pathogens in an amphibian community that experienced mass mortalities

Conservation Biology, Volume 38, Issue 3, June 2024.
Abstract Because host species tend to harbor multiple parasitic species, coinfection in a host is common. The chytrid fungus Batrachochytrium dendrobatidis (Bd) and the viruses in the genus Ranavirus (Rv) are responsible for the decline of amphibians worldwide.
Barbora Thumsová, Gonzalo Alarcos, Cesar Ayres, Gonçalo M. Rosa, Jaime Bosch   +4 more
wiley   +1 more source

The network structure of psychopathological and resilient responses to the pandemic: A multicountry general population study of depression and anxiety

Journal of Traumatic Stress, Volume 37, Issue 1, Page 126-140, February 2024.
Abstract Commonly identified patterns of psychological distress in response to adverse events are characterized by resilience (i.e., little to no distress), delayed (i.e., distress that increases over time), recovery (i.e., distress followed by a gradual decrease over time), and sustained (i.e., distress remaining stable over time). This study aimed to
Alba Contreras, Sarah Butter, Umberto Granziol, Anna Panzeri, Vanesa Peinado, Almudena Trucharte, Orestis Zavlis, Carmen Valiente, Carmelo Vázquez, Jamie Murphy, Marco Bertamini, Mark Shevlin, Todd K. Hartman, Giovanni Bruno, Giuseppe Mignemi, Andrea Spoto, Giulio Vidotto, Richard P. Bentall   +17 more
wiley   +1 more source

Subnotificação de eventos adversos ocasionados por medicamentos

Research, Society and Development, 2023
Os eventos adversos causados por medicamento afetam a segurança do paciente nas instituições de saúde, com isso a notificação é um fator de compromisso por parte dos profissionais de saúde para reduzir a ocorrência de erros. O objetivo é analisar possíveis causas de subnotificação de eventos adversos ocasionados por medicamentos.
Abraão Santos Sousa, Byanca Santana Sousa, Mirley Leticia Jesus Melo, Jéssica Damasceno de Santana, Yasmim Dória Cardoso Gois, Késsia Raianne Santos Carregosa, Andre Luis Albertoni, Hannah Sophia Vasconcelos Bezerra Silva, Francisco de Freitas Rego Neto, Jefferson Felipe Calazans Batista   +9 more
openaire   +1 more source